ZAK Produits
(Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))
Catégories
This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
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Catégories ZAK en vedette
ZAK Anticorps
High quality antibodies with extensive validation data.
ZAK Kits ELISA
Reliable ELISA kits for a wide range of species.
ZAK Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
ZAK recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (3)
- (5)
N° du produit
ABIN565679
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (4)
N° du produit
ABIN6150360
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC (p)
Validations
- (1)
- (2)
N° du produit
ABIN392643
Quantité
400 μL
Fiche technique
Fiche technique
ZAK recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1142997
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
N° du produit
ABIN5595441
Quantité
96 tests
Fiche technique
Fiche technique
ZAK recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (2)
N° du produit
ABIN1325564
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect cells (Sf21)
Validations
- (2)
N° du produit
ABIN5570540
Quantité
5 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1325566
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits ZAK
: "NEMO regulates a cell death switch in TNF signaling by inhibiting recruitment of RIPK3 to the cell death-inducing complex II." dans: Cell death & disease, Vol. 7, Issue 8, pp. e2346, (2017) (PubMed).: "A Requirement for ZAK Kinase Activity in Canonical TGF-β Signaling." dans: Translational oncology, Vol. 9, Issue 6, pp. 473-481, (2016) (PubMed).
: "Integrated exome and transcriptome sequencing reveals ZAK isoform usage in gastric cancer. ..." dans: Nature communications, Vol. 5, pp. 3830, (2014) (PubMed).
: "A-kinase anchoring protein Lbc coordinates a p38 activating signaling complex controlling compensatory cardiac hypertrophy." dans: Molecular and cellular biology, Vol. 33, Issue 15, pp. 2903-17, (2013) (PubMed).
: "A-kinase anchoring protein (AKAP)-Lbc anchors a PKN-based signaling complex involved in ?1-adrenergic receptor-induced p38 activation." dans: The Journal of biological chemistry, Vol. 286, Issue 10, pp. 7925-37, (2011) (PubMed).
: "Phosphoinositide 3-kinase signalling pathways." dans: Journal of cell science, Vol. 114, Issue Pt 8, pp. 1439-45, (2001) (PubMed).
: "Oncogenic kinase signalling." dans: Nature, Vol. 411, Issue 6835, pp. 355-65, (2001) (PubMed).
: "The RET proto-oncogene in human cancers." dans: Oncogene, Vol. 19, Issue 49, pp. 5590-7, (2000) (PubMed).
Synonymes et noms alternatifs relatifs à ZAK
mitogen-activated protein kinase kinase kinase 20 (Map3k20), mitogen-activated protein kinase kinase kinase 20 (MAP3K20), AV006891, AZK, B230120H23Rik, MLK7, mlklak, MLT, MLTK, MLTKalpha, MLTKbeta, MRK, pk, RGD1561394Protein level used designations for ZAK
- mitogen-activated protein kinase kinase kinase MLT
- HCCS-4
- MLK-like mitogen-activated protein triple kinase
- human cervical cancer suppressor gene 4 protein
- mixed lineage kinase 7
- mixed lineage kinase with a leucine zipper and a sterile alpha motif
- mixed lineage kinase-related kinase MRK-beta
- MLK-related kinase
- MRK
- leucine zipper- and sterile alpha motif kinase ZAK
- mixed lineage kinase-related kinase
- sterile alpha motif- and leucine zipper-containing kinase AZK
- sterile-alpha motif and leucine zipper containing kinase AZK
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