Cet anticorps anti-ZIC1-3 est un anticorps Lapin Polyclonal détectant ZIC1-3 dans IHC et WB. Adapté pour Humain.
N° du produit ABIN351417
Aperçu rapide pour ZIC1-3 anticorps (C-Term) (ABIN351417)
Antigène
ZIC1-3 (Zic1/2/3)
(Zic Family Member 1/2/3 (Zic1/2/3))
Reactivité
Humain
Hôte
Lapin
Clonalité
Polyclonal
Application
Immunohistochemistry (IHC), Western Blotting (WB)
Épitope
C-Term
Fonction
Rabbit antibody to ZIC1-3
Specificité
Specific for ZIC1 2 3.
Réactivité croisée
Humain, Souris, Rat
Réactivité croisée (Details)
Other species not yet tested.
Purification
IgG
Immunogène
A synthetic peptide from c-terminal region of human ZIC3 (Zinc finger protein ZIC 3) conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in many species including rat and mouse.
Isotype
IgG
Indications d'application
IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
Conseil sur la manipulation
Avoid freeze and thaw cycles.
Stock
4 °C,-20 °C
Stockage commentaire
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Date de péremption
12 months
Antigène
ZIC1-3 (Zic1/2/3)
(Zic Family Member 1/2/3 (Zic1/2/3))
Autre désignation
ZIC1-3
Sujet
Function: Probably functions as a transcription factor in the earliest stages of the left-right (LR) body axis formation. Defects in ZIC3 are the cause of X-linked visceral heterotaxy (HTX1). HTX1 is a disease characterized by congenital heart disease and alterations of visceral situs including asplenia or polysplenia symmetric liver intestinal malrotation and abnormal lung lobation.