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ZMPSTE24 Produits

(Zinc Metalloproteinase, Ste24 (Zmpste24))
This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy. [provided by RefSeq, Jul 2008].

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Catégories ZMPSTE24 en vedette

ZMPSTE24 Anticorps

High quality antibodies with extensive validation data.

ZMPSTE24 Kits ELISA

Reliable ELISA kits for a wide range of species.

ZMPSTE24 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

ZMPSTE24 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
N° du produit ABIN7146178
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
  • (2)
N° du produit ABIN389048
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
  • (2)
N° du produit ABIN389049
Quantité 400 μL
Fiche technique Fiche technique

ZMPSTE24 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method
Validations
N° du produit ABIN1124570
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1124571
Quantité 96 tests
Fiche technique Fiche technique

ZMPSTE24 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1325830
Quantité 2 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1325831
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN3124353
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits ZMPSTE24

Akinci, Sankella, Gilpin, Ozono, Garg, Agarwal: "Progeroid syndrome patients with ZMPSTE24 deficiency could benefit when treated with rapamycin and dimethylsulfoxide." dans: Cold Spring Harbor molecular case studies, Vol. 3, Issue 1, pp. a001339, (2017) (PubMed).

Afonso, Auclair, Boccara, Vantyghem, Katlama, Capeau, Vigouroux, Caron-Debarle: "LMNA mutations resulting in lipodystrophy and HIV protease inhibitors trigger vascular smooth muscle cell senescence and calcification: Role of ZMPSTE24 downregulation." dans: Atherosclerosis, Vol. 245, pp. 200-11, (2016) (PubMed).

Ponnusamy, Zhang, Kadam, Lin, Lim, Sandhu, Kothandaraman, Mahyuddin, Biswas, Venkat, Hew, Joshi, Chung, Choolani: "Membrane proteins of human fetal primitive nucleated red blood cells." dans: Journal of proteomics, Vol. 75, Issue 18, pp. 5762-73, (2012) (PubMed).

Fontaine-Bisson, Alessi, Saut, Fumeron, Marre, Dutour, Badens, Levy, Tichet, Juhan-Vague, Trégouët, Balkau, Morange: "Polymorphisms of the lamina maturation pathway and their association with the metabolic syndrome: the DESIR prospective study." dans: Journal of molecular medicine (Berlin, Germany), Vol. 88, Issue 2, pp. 193-201, (2010) (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." dans: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." dans: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).

Coffinier, Hudon, Farber, Chang, Hrycyna, Young, Fong: "HIV protease inhibitors block the zinc metalloproteinase ZMPSTE24 and lead to an accumulation of prelamin A in cells." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 33, pp. 13432-7, (2007) (PubMed).

Fong, Frost, Meta, Qiao, Yang, Coffinier, Young: "A protein farnesyltransferase inhibitor ameliorates disease in a mouse model of progeria." dans: Science (New York, N.Y.), Vol. 311, Issue 5767, pp. 1621-3, (2006) (PubMed).

Young, Fong, Michaelis: "Prelamin A, Zmpste24, misshapen cell nuclei, and progeria--new evidence suggesting that protein farnesylation could be important for disease pathogenesis." dans: Journal of lipid research, Vol. 46, Issue 12, pp. 2531-58, (2005) (PubMed).

Corrigan, Kuszczak, Rusinol, Thewke, Hrycyna, Michaelis, Sinensky: "Prelamin A endoproteolytic processing in vitro by recombinant Zmpste24." dans: The Biochemical journal, Vol. 387, Issue Pt 1, pp. 129-38, (2005) (PubMed).

Synonymes et noms alternatifs relatifs à ZMPSTE24

zinc metallopeptidase STE24 (ZMPSTE24), zinc metallopeptidase STE24 L homeolog (zmpste24.L), zinc metallopeptidase STE24 (zmpste24), CAAX prenyl protease (zmpste24), Peptidase family M48 family protein (ATSTE24), zinc metallopeptidase STE24 (Zmpste24), zinc metallopeptidase, STE24 (Zmpste24), zinc metallopeptidase, STE24 homolog (zmpste24), A530043O15Rik, D030046F19, DDBDRAFT_0189115, DDBDRAFT_0237846, DDB_0189115, DDB_0237846, F2N1.21, F2N1_21, FACE-1, Face-1, FACE1, fi45a02, HGPS, MADB, PRO1, STE24, Ste24p, wu:fi45a02, zgc:55655

Protein level used designations for ZMPSTE24

  • zinc metallopeptidase (STE24 homolog, S. cerevisiae)
  • zinc metallopeptidase (STE24 homolog)
  • zinc metallopeptidase STE24 homolog
  • zinc metalloproteinase STE24 homolog
  • CAAX prenyl protease 1 homolog
  • STE24 endopeptidase
  • zinc metalloproteinase
  • zinc metallopeptidase STE24
  • CAAX prenyl protease 1 homolog-like
  • farnesylated proteins-converting enzyme 1
  • prenyl protein-specific endoprotease 1
  • zinc metalloproteinase Ste24 homolog
  • zinc metallopeptidase, STE24 homolog
  • zinc metalloproteinase, STE24 homolog
  • farnesylated-proteins converting enzyme 1
  • zinc metalloproteinase (STE24 homolog, yeast)
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