CRHR1 anticorps (AA 250-263)
Aperçu rapide pour CRHR1 anticorps (AA 250-263) (ABIN190893)
Antigène
Voir toutes CRHR1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Épitope
- AA 250-263
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Fonction
- CRHR1 / CRF-R (aa 250 - 263)
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Séquence
- KLYYDNEKCW FGKR
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Réactivité croisée
- Boeuf (Vache), Chien, Humain, Souris, Rat, Mouton
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Purification
- Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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Immunogène
- Peptide with sequence KLYYDNEKCWFGKR, from the internal region of the protein sequence according to NP_004373.2.
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Isotype
- IgG
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Indications d'application
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Immunohistochemistry: Paraffin embedded Human Brain (Cortex). Recommended concentration: 5 μg/mL.
Western Blot: This antibody has been successfully used in WB on Mouse: Hunt AJ Jr et al, Brain Struct Funct. 2018 Jul,223(6):2685-2698. PMID: 29569009.
Peptide ELISA: antibody detection limit dilution 1:1000.
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Commentaires
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Immunofluorescence: Expression of the protein seen in the cytoplasm and vesicles of MCF7 cells. Recommended concentration: 10μg/ml.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Minimize freezing and thawing.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
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: "Paraventricular hypothalamic and amygdalar CRF neurons synapse in the external globus pallidus." dans: Brain structure & function, Vol. 223, Issue 6, pp. 2685-2698, (2019) (PubMed).
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- CRHR1 (Corticotropin Releasing Hormone Receptor 1 (CRHR1))
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Autre désignation
- CRHR1
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Sujet
- CRHR1, CRF-R, corticotropin releasing hormone receptor 1 , CRF1, CRFR1, CRH-R1h, CRHR, CRHR1f , corticotropin releasing hormone receptor variant 1h, seven transmembrane helix receptor
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ID gène
- 1394, 12921, 58959
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NCBI Accession
- NP_004373
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Pathways
- Hormone Transport, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Feeding Behaviour, Negative Regulation of Transporter Activity
Antigène
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