CRHR1 anticorps (AA 55-150)

N° du produit ABIN5675214

Détail du produit anti-CRHR1 anticorps

Antigène: CRHR1 (Corticotropin Releasing Hormone Receptor 1 (CRHR1))

Épitope: AA 55-150

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRHR1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Réactivité croisée: Souris, Rat

Homologie: Human

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CRHR1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur CRHR1

Antigène: CRHR1 (Corticotropin Releasing Hormone Receptor 1 (CRHR1))

Autre désignation: CRHR1 (CRHR1 Produits)

Synonymes: anticorps CRF-R, anticorps CRF-R-1, anticorps CRF-R1, anticorps CRF1, anticorps CRFR-1, anticorps CRFR1, anticorps CRH-R-1, anticorps CRH-R1, anticorps CRH-R1h, anticorps CRHR, anticorps CRHR1L, anticorps CRHR1f, anticorps Crhr, anticorps crhr1, anticorps crhr1-A, anticorps CRHR1, anticorps CRHR1-IT1-CRHR1, anticorps MGC57346-CRHR1, anticorps corticotropin releasing hormone receptor 1, anticorps corticotropin releasing hormone receptor 1, gene 2 S homeolog, anticorps corticotropin-releasing factor receptor 1, anticorps LINC02210-CRHR1 readthrough, anticorps CRHR1, anticorps Crhr1, anticorps crhr1.2.S, anticorps LOC610380, anticorps LOC100065598, anticorps LINC02210-CRHR1, anticorps crhr1

Sujet:

Synonyms: Corticotropin-releasing factor receptor 1, CRHR1, CRF-R-1, CRF-R1, CRFR-1, CRFR

Background: G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to stress. Plays a role in the response to anxiogenic stimuli.

ID gène: 1394

UniProt: P34998

Pathways: Hormone Transport, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Feeding Behaviour, Negative Regulation of Transporter Activity