BCL2L1 anticorps (AA 3-14)
Aperçu rapide pour BCL2L1 anticorps (AA 3-14) (ABIN135025)
Antigène
Voir toutes BCL2L1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 3-14
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Specificité
- Mouse/Rat/Human Bcl-xL
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Attributs du produit
- Mouse Anti-Bcl-xL-UNLB
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Purification
- Purified
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Immunogène
- Bcl-xL peptide (a.a. 3-14) common to mouse and human
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Isotype
- IgG2a
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anti-BCL2-Like 1 (BCL2L1) (AA 1-233) antibody
BCL2L1 Reactivité: Humain WB, IF, ELISA, PLA Hôte: Souris Monoclonal 3E2-2A5 unconjugated
anti-BCL2-Like 1 (BCL2L1) (AA 1-120) antibodyBCL2L1 Reactivité: Humain WB, IHC, IF, IP Hôte: Lapin Polyclonal unconjugated
anti-BCL2-Like 1 (BCL2L1) antibodyBCL2L1 Reactivité: Humain WB, IF, IP, ICC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-BCL2-Like 1 (BCL2L1) (AA 2-212) antibodyBCL2L1 Reactivité: Rat WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-BCL2-Like 1 (BCL2L1) (AA 2-212) antibodyBCL2L1 Reactivité: Humain WB, IHC, FACS, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-BCL2-Like 1 (BCL2L1) (AA 2-212) antibodyBCL2L1 Reactivité: Rat WB, IHC, IP, ICC Hôte: Souris Monoclonal C4 unconjugated
anti-BCL2-Like 1 (BCL2L1) (AA 1-233) antibodyBCL2L1 Reactivité: Humain WB, IF, PLA Hôte: Lapin Polyclonal unconjugated
anti-BCL2-Like 1 (BCL2L1) (AA 1-219) antibodyBCL2L1 Reactivité: Humain, Souris, Rat WB, IHC, IF, FACS, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-BCL2-Like 1 (BCL2L1) (pSer62) antibodyBCL2L1 Reactivité: Humain, Souris, Rat WB, IHC, IF, ELISA, ICC Hôte: Lapin Polyclonal unconjugated
anti-BCL2-Like 1 (BCL2L1) (N-Term) antibodyBCL2L1 Reactivité: Humain, Souris, Rat WB, IHC, IF, ELISA, ICC Hôte: Lapin Polyclonal unconjugated
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Indications d'application
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- Applications: WB - Quality tested , IP - Reported in literature , FC - Reported in literature , IHC-PS - Reported in literature , ELISA - Reported in literature
- Working Dilutions: Immunoblotting Purified (UNLB) antibody ≤ 2 g/mL
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Volume d'échantillon
- 1 mL
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Restrictions
- For Research Use only
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Concentration
- 0.1 mg/mL
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Buffer
- 0.1 mg of purified immunoglobulin in 1.0 mL of borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added
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Agent conservateur
- Without preservative
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Conseil sur la manipulation
- Each reagent is stable for the period shown on the bottle label if stored as directed.
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Stock
- 4 °C
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Stockage commentaire
- Store at 2-8°C
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- BCL2L1 (BCL2-Like 1 (BCL2L1))
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Autre désignation
- Bcl-xL
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Sujet
- Apoptosis, or programmed cell death, is a well-documented phenomenon in many cellular systems. It plays a key role in tissue and organ development as well as in adult tissues during cell turnover. Apoptosis can be induced by a variety of internal and external stimuli including growth factor deprivation, cytokine treatment, antigen-receptor engagement, cell-cell interactions, irradiation and glucocorticoid treatment. Bcl-2 and one of its homologues, Bcl-xL, protect cells from apoptosis, while other homologues of Bcl-2 such as Bax, Bad and Bak have been shown to enhance apoptosis. Bcl-xL has been shown to block apoptosis which is induced by a variety of stimuli and, under certain conditions, offers greater protection against apoptosis than Bcl-2. In contrast, Bad and Bax inhibit the protective functions of Bcl-xL and Bcl-2, respectively. Although heterodimerization between Bcl-xL/Bad and Bcl-2/Bax was originally thought to be essential for the differential anti-apoptotic activity of Bcl-xL and Bcl-2, other results suggest that the formation of heterodimers may not be necessary for this death-repressing activity.
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Pathways
- Apoptose, Negative Regulation of intrinsic apoptotic Signaling
Antigène
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