MYL2 anticorps
Aperçu rapide pour MYL2 anticorps (ABIN969302)
Antigène
Voir toutes MYL2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- MYL2 Antibody
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Purification
- Ascitic fluid
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Immunogène
- Purified recombinant fragment of MYL2 expressed in E. Coli.
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Isotype
- IgG1
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Indications d'application
- ELISA: 1/10000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Ascitic fluid containing 0.03 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Human fast skeletal myosin light chain 2 cDNA: isolation, tissue specific expression of the single copy gene, comparative sequence analysis of isoforms and evolutionary relationships." dans: DNA sequence : the journal of DNA sequencing and mapping, Vol. 14, Issue 5, pp. 339-50, (2004) (PubMed).
: "Rho-kinase contributes to diphosphorylation of myosin II regulatory light chain in nonmuscle cells." dans: Oncogene, Vol. 21, Issue 38, pp. 5852-60, (2002) (PubMed).
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- MYL2 (Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2))
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Autre désignation
- MYL2
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Sujet
- MYL2(myosin, light chain 2, regulatory, cardiac, slow), also known as MLC-2, MLC2v. Entrez protein NP_000423. MYL2 associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. It is an hexamer of two heavy chains and four light chains that is predominantly expressed in adult cardiac ventricle muscle. Mutations in MYL2 are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.
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Poids moléculaire
- 19 kDa
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ID gène
- 4633
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UniProt
- P10916
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Pathways
- Myometrial Relaxation and Contraction
Antigène
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