MYL2 anticorps (AA 8-164)

N° du produit ABIN7160551

Détail du produit anti-MYL2 anticorps

Antigène: MYL2 (Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2))

Épitope: AA 8-164

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYL2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Myosin regulatory light chain 2, ventricular/cardiac muscle isoform protein (8-164AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MYL2

Antigène: MYL2 (Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2))

Autre désignation: MYL2 (MYL2 Produits)

Synonymes: anticorps CMH10, anticorps MLC2, anticorps 2410014J02Rik, anticorps MLC-2, anticorps Mlc2, anticorps MLC-2v, anticorps Mlc2v, anticorps Mylpc, anticorps Mlc-2, anticorps myl2, anticorps zgc:136848, anticorps XMLC2, anticorps cmh10, anticorps mlc2, anticorps G2, anticorps MLC-2A, anticorps MLC2V, anticorps myosin light chain 2, anticorps myosin light chain, phosphorylatable, fast skeletal muscle, anticorps myosin, light polypeptide 2, regulatory, cardiac, slow, anticorps myosin, light chain 2b, regulatory, cardiac, slow, anticorps myosin light chain 2 S homeolog, anticorps myosin, light chain 2, regulatory, cardiac, slow, anticorps MYL2, anticorps Mylpf, anticorps Myl2, anticorps myl2b, anticorps myl2.S

Sujet:

Background: Contractile protein that plays a role in heart development and function. Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion, as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin binding sites to sustain thin filament activation as a means to fine-tune myofilament calcium sensitivity to force. During cardiogenesis plays an early role in cardiac contractility by promoting cardiac myofibril assembly.

Aliases: Cardiac myosin light chain-2 antibody, Cardiac ventricular myosin light chain 2 antibody, CMH10 antibody, MLC 2v antibody, MLC-2 antibody, MLC-2v antibody, MLC2 antibody, MLRV_HUMAN antibody, MYL 2 antibody, MYL2 antibody, Myosin light chain 2 regulatory cardiac slow antibody, Myosin light polypeptide 2 regulatory cardiac slow antibody, Myosin regulatory light chain 2 antibody, Myosin regulatory light chain 2 ventricular/cardiac muscle isoform antibody, Regulatory light chain of myosin antibody, RLC of myosin antibody, Slow cardiac myosin regulatory light chain 2 antibody, ventricular/cardiac muscle isoform antibody

UniProt: P10916

Pathways: Myometrial Relaxation and Contraction