XRCC6 anticorps
Aperçu rapide pour XRCC6 anticorps (ABIN187448)
Antigène
Voir toutes XRCC6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Reacts with the p70 Ku antigen subunit. Recognizes an epitope between aa 506-541 of p70. Species Reactivity: Human, monkey and Xenopus. Mouse and hamster (Western blots only). Does not react with bovine, rabbit or sea urchin. Other species not tested. Cellular Location: Nuclear.Positive Control: BT474, T47D, HEP-G-2 or HeLa cells. Tonsil.
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Immunogène
- Human placental extract designated as PSE1-PL.
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Isotype
- IgG2b
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anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (C-Term) antibody
XRCC6 Reactivité: Humain WB, IF, IHC (p), ICC, IP, PLA Hôte: Lapin Polyclonal unconjugated
anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (AA 1-609) antibodyXRCC6 Reactivité: Humain WB, ELISA, IF, IHC (p) Hôte: Souris Monoclonal 4C2-1A6 unconjugated
anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (AA 397-603) antibodyXRCC6 Reactivité: Rat WB, IHC, ICC, IP Hôte: Lapin Polyclonal unconjugated
anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (AA 319-538) antibodyXRCC6 Reactivité: Souris WB, IHC, ICC, IP Hôte: Lapin Polyclonal unconjugated
anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (AA 521-548), (C-Term) antibodyXRCC6 Reactivité: Humain WB, IF, FACS, IHC (p) Hôte: Lapin Polyclonal RB20806 unconjugated
anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (AA 408-609) antibodyXRCC6 Reactivité: Humain WB, IHC, IF, IP Hôte: Lapin Polyclonal unconjugated
anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (AA 6-214) antibodyXRCC6 Reactivité: Humain WB, IHC, ELISA, FACS, ICC Hôte: Souris Monoclonal 2F7F5 unconjugated
anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (acLys542) antibodyXRCC6 Reactivité: Humain WB, ELISA, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) antibodyXRCC6 Reactivité: Humain, Souris, Rat WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (AA 521-548) antibodyXRCC6 Reactivité: Humain WB, IHC, ELISA, IF, FACS Hôte: Lapin Polyclonal unconjugated
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Indications d'application
- Immunofluorescence Immunohistochemistry: (Formalin/paraffin) Use at a 1:400 dilution for 30 minutes at room temperature (RT). Staining of formalin-fixed tissues is improved by boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min. followed by cooling to RT for 20 min. Immunoprecipitation: (Native and denatured) Use at 2 µg/mg protein lysate. Use Protein A. Western blot: Use at 0.25-0.5 µg/mL for 2 hrs. at RT. The optimal dilution for a specific application should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 100 µg of monoclonal antibody at 200 µg/mL in 10 mM PBS, pH 7.4, with protein stabilizer and 0.09% sodium azide. Purified from ascites fluid by Protein A chromatography.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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- XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))
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Autre désignation
- XRCC6 / Ku70
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Sujet
- The Ku autoantigen is a heterodimer of 70 kDa (p70) and ~80 kDa (p80) proteins. The p70/p80 dimer is important for the function of a 460 kDa DNA-dependent protein kinase that phosphorylates certain transcription factors, including Sp1, Oct-1, p53 and SV40 large T antigen in vitro. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation and apoptosis.
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Pathways
- Réparation de l'ADN
Antigène
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