ALDH1A1 anticorps (Middle Region)
Aperçu rapide pour ALDH1A1 anticorps (Middle Region) (ABIN633157)
Antigène
Voir toutes ALDH1A1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Specificité
- ALDH1 A1 antibody was raised against the middle region of ALDH1 1
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Purification
- Affinity purified
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Immunogène
- ALDH1 A1 antibody was raised using the middle region of ALDH1 1 corresponding to a region with amino acids SVERAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGG
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Indications d'application
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
Commentaires
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ALDH1A1 Blocking Peptide, (ABIN5612008), is also available for use as a blocking control in assays to test for specificity of this ALDH1A1 antibody
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of ALDH0 1 antibody in PBS
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Concentration
- Lot specific
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Buffer
- PBS
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Conseil sur la manipulation
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))
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Autre désignation
- ALDH1A1
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Sujet
- This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a cytosolic isoform, which has a high affinity for aldehydes.
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Poids moléculaire
- 55 kDa (MW of target protein)
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Pathways
- Dopaminergic Neurogenesis
Antigène
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