JAG1 anticorps (AA 110-125)
Aperçu rapide pour JAG1 anticorps (AA 110-125) (ABIN401024)
Antigène
Voir toutes JAG1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 110-125
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Specificité
- This protein A purified antibody is directed against Human Jagged-1 protein. Expect a band approximately 150 kDa in size corresponding to Jagged-1 in Mouse liver whole cell lysates, and a 75 kDa band in Human brain and kidney lysates. A BLAST analysis was used to suggest cross reactivity with Jagged-1 protein from Human, Chimpanzee, Rat and Mouse based on 100 % homology with the immunizing sequence. Partial reactivity is expected against dog (81 %) and Xenopus laevis (85 %) based on partial sequence homologies as indicated. Reactivity against homologues from other sources is not known.
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Réactivité croisée (Details)
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Species reactivity (expected):Chimpanzee, Rat.
Species reactivity (tested):Human and Mouse. -
Purification
- Affinity Chromatography on Protein A.
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Immunogène
- Synthetic peptide corresponding to amino acids 110-125 of Human Jagged-1 protein.
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Isotype
- IgG
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anti-Jagged 1 (JAG1) (N-Term) antibody
JAG1 Reactivité: Humain, Souris WB, IHC, ELISA, IF, FM Hôte: Lapin Polyclonal unconjugated
anti-Jagged 1 (JAG1) (AA 47-212) antibodyJAG1 Reactivité: Humain WB, ELISA, FACS Hôte: Souris Monoclonal 7C7H2 unconjugated
anti-Jagged 1 (JAG1) (Internal Region) antibodyJAG1 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF Hôte: Lapin Polyclonal unconjugated
anti-Jagged 1 (JAG1) (AA 47-212) antibodyJAG1 Reactivité: Humain ELISA, FACS Hôte: Souris Monoclonal 6A9B2 unconjugated
anti-Jagged 1 (JAG1) (AA 836-1047) antibodyJAG1 Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Jagged 1 (JAG1) (AA 809-1046) antibodyJAG1 Reactivité: Humain IHC, ELISA, IF Hôte: Lapin Polyclonal unconjugated
anti-Jagged 1 (JAG1) antibodyJAG1 Reactivité: Humain WB, IHC, ELISA, FACS Hôte: Souris Monoclonal J1G53-3 unconjugated
anti-Jagged 1 (JAG1) (AA 826-1084) antibodyJAG1 Reactivité: Souris WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Jagged 1 (JAG1) (AA 470-834) antibodyJAG1 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
anti-Jagged 1 (JAG1) (AA 33-250) antibodyJAG1 Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
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Indications d'application
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Suitable for use in ELISA, Immunohistochemistry, Immunofluorescence microscopy andWestern blot. Recommended Dilutions: ELISA: 1/20,000-1/100,000. Western Blot: 1/500-1/2,000. Immunofluorescence: 1/200-1/1,000. Immunohistochemistry on Paraffin Sections: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL (by UV absorbance at 280 nm)
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Buffer
- 0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2, 0.01 % (w/v) Sodium Azide, None
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- -20 °C
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Stockage commentaire
- Store the antibody (in aliquots) at-20 °C.
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- JAG1 (Jagged 1 (JAG1))
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Autre désignation
- CD339 / JAG1
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Sujet
- Jagged 1 protein encoded by the JAG1 gene, that is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the Jagged 1 protein cause Alagille syndrome. Jagged 1 signaling through notch 1 has also been shown to play a role in hematopoies.Synonyms: JAGL1, Jagged-1, hJ1
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ID gène
- 182
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NCBI Accession
- NP_000205
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UniProt
- P78504
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Pathways
- Signalisation Notch, Stem Cell Maintenance
Antigène
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