GNAI1 anticorps (Middle Region)
Aperçu rapide pour GNAI1 anticorps (Middle Region) (ABIN406409)
Antigène
Voir toutes GNAI1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- Middle Region
-
Séquence
- YQLNDSAAYY LNDLDRIAQP NYIPTQQDVL RTRVKTTGIV ETHFTFKDLH
-
Homologie
- Cow: 100%, Dog: 100%, Goat: 79%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 79%, Yeast: 100%, Zebrafish: 85%
-
Attributs du produit
- This is a rabbit polyclonal antibody against GNAI1. It was validated on Western Blot using a cell lysate as a positive control.
-
Purification
- Affinity Purified
-
Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human GNAI1
-
-
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1) (AA 1-354) antibody
GNAI1 Reactivité: Humain WB, ELISA, IHC (p) Hôte: Souris Monoclonal 2B8-2A5 unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1) (AA 1-355) antibodyGNAI1 Reactivité: Humain WB, ELISA, IHC, IHC (p) Hôte: Souris Monoclonal 2B8-2A5 unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1) (AA 1-354) antibodyGNAI1 Reactivité: Humain WB, ELISA Hôte: Souris Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1) antibodyGNAI1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye WB, IHC, IHC (p) Hôte: Souris Monoclonal R4-5 unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1) (Center) antibodyGNAI1 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1) antibodyGNAI1 Reactivité: Humain, Souris, Rat ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1) (AA 1-354) antibodyGNAI1 Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1) (AA 146-195) antibodyGNAI1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc, Chien, Lapin, Poisson zèbre (Danio rerio), Drosophila melanogaster, Hamster, Singe, Roussette (Chauve-souris) WB Hôte: Lapin Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1) antibodyGNAI1 Reactivité: Humain, Souris, Rat, Drosophila melanogaster WB Hôte: Lapin Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1) (Middle Region) antibodyGNAI1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc, Cobaye, Chien, Lapin, Poisson zèbre (Danio rerio), Cheval, Chévre, Saccharomyces cerevisiae, Mouton WB Hôte: Lapin Polyclonal unconjugated
-
-
Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
-
Commentaires
-
Antigen size: 354 AA
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- Lot specific
-
Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- GNAI1 (Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1))
-
Autre désignation
- GNAI1
-
Sujet
-
Guanine nucleotide-binding proteins (G proteins) form a large family of signal-transducing molecules. They are found as heterotrimers made up of alpha, beta, and gamma subunits. Members of the G protein family have been characterized most extensively on the basis of the alpha subunit, which binds guanine nucleotide, is capable of hydrolyzing GTP, and interacts with specific receptor and effector molecules. The G protein family includes Gs and Gi, the stimulatory and inhibitory GTP-binding regulators of adenylate cyclase, Go, a protein abundant in brain (GNAO1), and transducin-1 (GNAT1) and transducin-2 (GNAT2), proteins involved in phototransduction in retinal rods and cones, respectively.Guanine nucleotide-binding proteins (G proteins) form a large family of signal-transducing molecules. They are found as heterotrimers made up of alpha, beta, and gamma subunits. Members of the G protein family have been characterized most extensively on the basis of the alpha subunit, which binds guanine nucleotide, is capable of hydrolyzing GTP, and interacts with specific receptor and effector molecules. The G protein family includes Gs (MIM 139320) and Gi, the stimulatory and inhibitory GTP-binding regulators of adenylate cyclase, Go, a protein abundant in brain (GNAO1, MIM 139311), and transducin-1 (GNAT1, MIM 139330) and transducin-2 (GNAT2, MIM 139340), proteins involved in phototransduction in retinal rods and cones, respectively (Sullivan et al., 1986 [PubMed 3092218], Bray et al., 1987 [PubMed 3110783]). Suki et al. (1987) [PubMed 2440724] concluded that the human genome contains at least 3 nonallelic genes for alpha-i-type subunits of G protein, see, e.g, GNAI2 (MIM 139360), GNAI3 (MIM 139370), and GNAIH (MIM 139180).[supplied by OMIM]. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: Gi
Protein Interaction Partner: GPSM3, RGS17, ESR1, ATP4A, RAD52, SVIL, NUCB1, NCF2, MTNR1B, MTNR1A, NCF1, THAP7, RIC8A, RGS14, IQCB1, UBC, RANGAP1, GPR50, GNB1, GNAI3, GNAI2, GNB4, GNB2, PTH1R, PCK1, Haus1, Cep76, Haus4, Recql4, Trim69, Cbx1, PGR, STRN, KLHL3, ADCY5, RASD1, CRHR1, GPSM
Protein Size: 354 -
Poids moléculaire
- 40 kDa
-
ID gène
- 2770
-
NCBI Accession
- NM_002069, NP_002060
-
UniProt
- P63096
-
Pathways
- G-protein mediated Events
Antigène
-
