Kv2.1/KCNB1 anticorps (Middle Region)
Aperçu rapide pour Kv2.1/KCNB1 anticorps (Middle Region) (ABIN404910)
Antigène
Voir toutes Kv2.1/KCNB1 (KCNB1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- YIDADTDDEG QLLYSVDSSP PKSLPGSTSP KFSTGTRSEK NHFESSPLPT
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Homologie
- Cow: 92%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Pig: 93%, Rat: 86%
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Attributs du produit
- This is a rabbit polyclonal antibody against KCNB1. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human KCNB1
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 858 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Kv2.1/KCNB1 (KCNB1) (Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 1 (KCNB1))
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Autre désignation
- KCNB1
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Sujet
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Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members.Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DRK1, KV2.1, h-DRK1
Protein Interaction Partner: STX1A, KCNG3, KCNG4, KCNV1, KCNB2, KCNG1, KCNB1, SRC, SUMO1, NEDD4L, KCNV2, KCNG2, KCNS3, PTPRE, SNAP25, KCNH1,
Protein Size: 858 -
Poids moléculaire
- 96 kDa
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ID gène
- 3745
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NCBI Accession
- NM_004975, NP_004966
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UniProt
- Q14721
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Pathways
- Synaptic Membrane
Antigène
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