Kv2.1/KCNB1 anticorps (C-Term)

N° du produit ABIN6658107

Détail du produit anti-Kv2.1/KCNB1 anticorps

Antigène: Kv2.1/KCNB1 (KCNB1) (Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 1 (KCNB1))

Épitope: C-Term

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Kv2.1/KCNB1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Fluorescence Microscopy (FM)

Réactivité croisée: Humain, Souris, Rat (Rattus)

Purification: Anti-Kv2.1 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Kv2.1 from Mouse, Human, and Rat based on 100% homology with the immunizing sequence. No cross reactivity to rat Kv2.2. Cross-reactivity with Kv2.1 from other sources has not been determined. Ion Channels research.

Immunogène:

Immunogen: Kv2.1 Antibody was produced in mice by repeated immunizations raised against a synthetic peptide corresponding to the cytoplasmic C-terminus region of rat KV2.1.

Immunogen Type: Peptide

Clone: S89-34

Isotype: IgG1

Information d'application

Indications d'application:

Immunohistochemistry Dilution: 0.1-1.0 μg/mL

Application Note: Anti-Kv2.1 Antibody is suitable for use in WB, IP, and IHC. Expect a band approximately ~105-125 kDa on specific lysates (varies with cell background due to phosphorylation). Specific conditions for reactivity should be optimized by the end user.

Immunoprecipitation Dilution: User Optimized

Western Blot Dilution: 1 μg/mL

IF Microscopy Dilution: 1.0-10 μg/mL

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Stock: RT,4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Détails sur Kv2.1/KCNB1

Antigène: Kv2.1/KCNB1 (KCNB1) (Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 1 (KCNB1))

Autre désignation: Kv2.1 (KCNB1 Produits)

Synonymes: anticorps KCNB1, anticorps Kcnb1, anticorps Kcr1-1, anticorps Kv2.1, anticorps Shab, anticorps DRK1PC, anticorps DRK1, anticorps KV2.1, anticorps h-DRK1, anticorps potassium voltage-gated channel subfamily B member 1, anticorps potassium voltage-gated channel, Shab-related subfamily, member 1, anticorps potassium channel, voltage gated Shab related subfamily B, member 1, anticorps potassium voltage gated channel, Shab-related subfamily, member 1, anticorps KCNB1, anticorps kcnb1, anticorps LOC100541632, anticorps Kcnb1

Sujet:

Synonyms: Shab, Kv2.1, DRK1PC, Kcr1-1, Kcnb1, Potassium voltage-gated channel subfamily B member 1, Delayed rectifier potassium channel 1, DRK1, Voltage-gated potassium channel subunit Kv2.1

Background: Voltage gated channels are tetrameters composed of four alpha-subunits arranged around a central pore. Each alpha subunit consists of six transmembrane segments with cytoplasmic NH2 and COOH-termini. Members of the KV1- KV4 subfamilies generate functional K+ channels in a homotetrameric configuration. The KV2 subfamily consists of KV2.1 and KV2.2, and both have very similar properties. Members of the KV2 subfamily are widely expressed in neuronal tissues. They have also been reported in neurons in the dorsal root ganglia.

Gene Name: Kcnb1

ID gène: 25736

NCBI Accession: NP_037318

UniProt: P15387

Pathways: Synaptic Membrane