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RFC3 anticorps (N-Term)

L’anticorps anti-RFC3 Polyclonal Lapin est utilisé pour la détection de RFC3 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Cobaye et Lapin. Il a été validé pour WB.
N° du produit ABIN310766
150,78 €
Plus frais de livraison 40,00 € et TVA
Destination: France
Envoi sous 6 à 9 jours ouvrables

Aperçu rapide pour RFC3 anticorps (N-Term) (ABIN310766)

Antigène

Voir toutes RFC3 Anticorps
RFC3 (Replication Factor C (Activator 1) 3, 38kDa (RFC3))

Reactivité

  • 32
  • 14
  • 12
  • 7
  • 6
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Cobaye, Lapin

Hôte

  • 26
  • 6
Lapin

Clonalité

  • 29
  • 3
Polyclonal

Conjugué

  • 32
Cet anticorp RFC3 est non-conjugé

Application

  • 31
  • 12
  • 8
  • 8
  • 6
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB)
  • Épitope

    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Séquence

    YHLEVNPSDA GNSDRVVIQE MLKTVAQSQQ LETNSQRDFK VVLLTEVDKL

    Homologie

    Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%

    Attributs du produit

    This is a rabbit polyclonal antibody against RFC3. It was validated on Western Blot using a cell lysate as a positive control.

    Purification

    Affinity Purified

    Immunogène

    The immunogen is a synthetic peptide directed towards the N terminal region of human RFC3
  • Indications d'application

    Optimal working dilutions should be determined experimentally by the investigator.

    Commentaires

    Antigen size: 356 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène

    RFC3 (Replication Factor C (Activator 1) 3, 38kDa (RFC3))

    Autre désignation

    RFC3

    Sujet

    The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. RFC3 is the 38 kDa subunit. This subunit is essential for the interaction between the 140 kDa subunit and the core complex that consists of the 36, 37, and 40 kDa subunits.The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 38 kD subunit. This subunit is essential for the interaction between the 140 kD subunit and the core complex that consists of the 36, 37, and 40 kD subunits. Alternatively spliced transcript variants encoding distinct isoforms have been described.
    Alias Symbols: MGC5276, RFC38
    Protein Interaction Partner: PCNA, TP53, UBC, RPA3, RPA2, RPA1, RPP40, FBXO6, ARFGAP1, VCP, RFC4, RFC5, RFC2, RFC1, PURB, PURA, MCM3, Cebpb, RAD21, HDGF, SMARCAD1, EBNA-LP, MESDC2, MYC, FAN1, MEPCE, USP20, CHTF8, RAD17, BRD4, CHTF18,
    Protein Size: 356

    Poids moléculaire

    40 kDa

    ID gène

    5983

    NCBI Accession

    NM_002915, NP_002906

    UniProt

    P40938

    Pathways

    Telomere Maintenance, Réparation de l'ADN, DNA Replication, Synthesis of DNA
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