Pour une meilleure utilisation, nous vous conseillons d’activer Javascript dans votre navigateur.

ABCB1 anticorps (AA 255-280)

Il existe 1 publication pour ce produit. L’anticorps anti-ABCB1 Polyclonal Lapin est utilisé pour la détection de ABCB1 dans des échantillons de Humain. Il a été validé pour WB, IHC et ELISA.

Western blot using affinity purified anti-ABCB1 antibody shows detection of ABCB1 in crude membrane extracts from HF insect cells over-expressing human ABCB1. (ABCB1 anticorps (AA 255-280))

IHC using ABCB1 Antibody at 20 ug/ml against FFPE human kidney. (ABCB1 anticorps (AA 255-280))

IHC

2 images

(1 reference)

N° du produit ABIN129711

N° du produit (Fournisseur): 600-401-967

624,85 €

Frais d'envoi 40,00 €, glace carbonique 20,00 € et TVA exclus

Destination: France

Envoi sous 5 à 8 jours ouvrables

Aperçu rapide pour ABCB1 anticorps (AA 255-280) (ABIN129711)

Antigène

Voir toutes ABCB1 Anticorps

ABCB1 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))

Reactivité

Humain

Hôte

Lapin

Clonalité

Polyclonal

Conjugué

Cet anticorp ABCB1 est non-conjugé

Application

Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Discover our top product ABCB1 Anticorps primaire

Épitope
6

5

5

4

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 255-280

N° du produit (Fournisseur)

600-401-967

Fournisseur

Rockland

Fonction

ABCB1 Antibody

Réactivité croisée (Details)

This affinity-purified antibody is directed against human ABCB1 protein.

Attributs du produit

Synonyms: rabbit anti-ABCB1 Antibody, ABCB 1, ABCB-1, ATP binding cassette sub family B MDR/TAP member 1 antibody, CD243 antibody, CD243 antigen antibody, CLCS antibody, GP170 antibody, MDR 1 antibody

Purification

The product was affinity purified from monospecific antiserum by immunoaffinity chromatography.

Stérilité

Sterile filtered

Immunogène

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near amino acids 255-280 of human ABCB1 protein.
Immunogen Type: Conjugated Peptide

Isotype

IgG
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (AA 621-650), (Middle Region) antibody
ABCB1 Reactivité: Humain, Souris, Rat IHC Hôte: Lapin Polyclonal unconjugated

anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (AA 995-1280) antibody
ABCB1 Reactivité: Humain WB, IHC, IHC (p) Hôte: Souris Monoclonal 2C7 unconjugated

anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) antibody
ABCB1 Reactivité: Humain WB, IHC Hôte: Lapin Monoclonal unconjugated

anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (AA 995-1280) antibody
ABCB1 Reactivité: Humain IHC, IHC (p) Hôte: Souris Monoclonal 5B3 unconjugated

anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (AA 236-297) antibody
ABCB1 Reactivité: Humain IHC, ELISA, IF Hôte: Lapin Polyclonal unconjugated

anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (AA 1149-1280) antibody
ABCB1 Reactivité: Humain ELISA, FACS Hôte: Souris Monoclonal 4G6F4 unconjugated

anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (AA 632-693) antibody
ABCB1 Reactivité: Humain ELISA Hôte: Souris Monoclonal 6G11C12 unconjugated

anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) antibody
KD Validated ABCB1 Reactivité: Humain WB, IF (p) Hôte: Lapin Monoclonal 23GB1330 unconjugated Recombinant Antibody

anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (AA 863-912) antibody
ABCB1 Reactivité: Humain, Souris, Rat, Hamster, Lapin WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated

anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (Internal Region) antibody
ABCB1 Reactivité: Humain, Souris, Rat WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated

Indications d'application

Immunohistochemistry Dilution: User Optimized
Application Note: This affinity purified antibody has been tested for use in ELISA, immunohistochemistry, and western blot.
Western Blot Dilution: 1:200 - 1:2,000
ELISA Dilution: 1:10,000 - 1:50,000
Other: User Optimized

Restrictions

For Research Use only
Format

Liquid

Concentration

1.0 mg/mL

Buffer

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

4 °C,-20 °C

Stockage commentaire

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption

12 months
Al-Shawi, Omote: "The remarkable transport mechanism of P-glycoprotein: a multidrug transporter." dans: Journal of bioenergetics and biomembranes, Vol. 37, Issue 6, pp. 489-96, (2006) (PubMed).
Antigène

ABCB1 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))

Autre désignation

ABCB1

Sujet

Background: This antibody is designed, produced, and validated as part of a collaboration with the National Cancer Institute (NCI) and is suitable for Cancer, Immunology and Nuclear Signaling research. ATP-Binding Cassette Sub-Family B Member 1 (ABCB1, also named P-glycoprotein) is a plasma membrane-associated multidrug transporter that utilizes the energy of ATP hydrolysis to pump toxic xenobiotics out of cells. Unique features of ABCB1 are its very broad substrate specificity and its basal ATPase activity in the absence of transport substrates. Human ABCB1 plays an important role in absorption, distribution, metabolism, excretion and toxicity of pharmacologically relevant drugs. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anti-cancer drugs. This protein also functions as a transporter across the blood-brain barrier.

ID gène

5243, 42741659

UniProt

P08183