ABCB1 anticorps (Internal Region)
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- Antigène Voir toutes ABCB1 Anticorps
- ABCB1 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))
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Épitope
- Internal Region
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ABCB1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Specificité
- P Glycoprotein 1(MDR1) Antibody detects endogenous levels of total P Glycoprotein 1(MDR1).
- Homologie
- Pig,Horse,Rabbit,Dog,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human P Glycoprotein 1(MDR1), corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product ABCB1 Anticorps primaire
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- Indications d'application
- WB 1:500-1:1000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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MicroRNA-139-5p affects cisplatin sensitivity in human nasopharyngeal carcinoma cells by regulating the epithelial-to-mesenchymal transition." dans: Gene, Vol. 652, pp. 48-58, (2018) (PubMed).
: "Increased autophagy in EOC re-ascites cells can inhibit cell death and promote drug resistance." dans: Cell death & disease, Vol. 9, Issue 4, pp. 419, (2018) (PubMed).
: "Brusatol Enhances the Chemotherapy Efficacy of Gemcitabine in Pancreatic Cancer via the Nrf2 Signalling Pathway." dans: Oxidative medicine and cellular longevity, Vol. 2018, pp. 2360427, (2018) (PubMed).
: "miR-506 enhances the sensitivity of human colorectal cancer cells to oxaliplatin by suppressing MDR1/P-gp expression." dans: Cell proliferation, Vol. 50, Issue 3, (2017) (PubMed).
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MicroRNA-139-5p affects cisplatin sensitivity in human nasopharyngeal carcinoma cells by regulating the epithelial-to-mesenchymal transition." dans: Gene, Vol. 652, pp. 48-58, (2018) (PubMed).
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- Antigène
- ABCB1 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))
- Autre désignation
- ABCB1 (ABCB1 Produits)
- Synonymes
- anticorps ABC20, anticorps CD243, anticorps CLCS, anticorps GP170, anticorps MDR1, anticorps P-GP, anticorps PGY1, anticorps Abcb1, anticorps Mdr1a, anticorps p-gp, anticorps xemdr, anticorps Mdr1, anticorps Mdr1b, anticorps Pgy-1, anticorps Pgy1, anticorps mdr, anticorps ABCB1, anticorps PGP1, anticorps ATP binding cassette subfamily B member 1, anticorps ATP binding cassette subfamily B member 1A, anticorps ATP binding cassette subfamily B member 1 L homeolog, anticorps ATP-binding cassette, sub-family B (MDR/TAP), member 1B, anticorps ABCB1, anticorps Abcb1a, anticorps abcb1.L, anticorps Abcb1b, anticorps Abcb1
- Sujet
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Description: Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
Gene: ABCB1
- Poids moléculaire
- 141 kDa
- ID gène
- 5243
- UniProt
- P08183
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