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ACVRL1 anticorps (N-Term)

Cité dans 4 publications. Cet anticorps anti-ACVRL1 Polyclonal Lapin (Clone RB03736) (ABIN392241) détecte spécifiquement ACVRL1 dans WB, FACS et IHC (p). L’anticorps est réactif avec des échantillons de Humain et Souris.

Flow cytometric analysis of HepG2 cells using ACVRL1 Antibody (N-term) (bottom histogram) compared to a negative control cell (top histogram). (ACVRL1 anticorps (N-Term))

FACS

Western blot of ACVRL1 Pab (ABIN392241 and ABIN2841932). (ACVRL1 anticorps (N-Term))

Western blot analysis of ACVRL1 (arrow) using rabbit polyclonal ACVRL1 Antibody (N-term) (ABIN392241 and ABIN2841932). (ACVRL1 anticorps (N-Term))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (ACVRL1 anticorps (N-Term))

IHC (p)

5 images

(4 références)

N° du produit ABIN392241

534,00 €

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Destination: France

Envoi sous 5 à 7 jours ouvrables

Aperçu rapide pour ACVRL1 anticorps (N-Term) (ABIN392241)

Antigène

Voir toutes ACVRL1 Anticorps

ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))

Reactivité

Humain, Souris

Hôte

Lapin

Clonalité

Polyclonal

Conjugué

Cet anticorp ACVRL1 est non-conjugé

Application

Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

RB03736

Épitope
8

8

7

6

6

3

2

1

1

1

1

1

1

1

1

1

1

1

1
AA 38-68, N-Term

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène

This ACVRL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-68 amino acids from the N-terminal region of human ACVRL1.

Isotype

Ig Fraction
anti-Activin A Receptor Type II-Like 1 (ACVRL1) (AA 38-68) antibody
ACVRL1 Reactivité: Humain, Souris WB, ELISA, IHC, FACS Hôte: Lapin Polyclonal unconjugated

anti-Activin A Receptor Type II-Like 1 (ACVRL1) antibody
ACVRL1 Reactivité: Humain WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated

anti-Activin A Receptor Type II-Like 1 (ACVRL1) (AA 271-362) antibody
ACVRL1 Reactivité: Humain, Souris, Rat WB, ELISA, IHC, FACS Hôte: Lapin Polyclonal unconjugated

anti-Activin A Receptor Type II-Like 1 (ACVRL1) (C-Term) antibody
ACVRL1 Reactivité: Humain, Souris WB, IHC (p) Hôte: Lapin Polyclonal unconjugated

anti-Activin A Receptor Type II-Like 1 (ACVRL1) antibody
ACVRL1 Reactivité: Humain WB, IF Hôte: Lapin Monoclonal unconjugated

anti-Activin A Receptor Type II-Like 1 (ACVRL1) (Internal Region) antibody
ACVRL1 Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated

anti-Activin A Receptor Type II-Like 1 (ACVRL1) (AA 89-103), (Extracellular) antibody
ACVRL1 Reactivité: Souris WB, FACS, LCI Hôte: Lapin Polyclonal unconjugated

anti-Activin A Receptor Type II-Like 1 (ACVRL1) (Internal Region) antibody
ACVRL1 Reactivité: Humain, Souris WB Hôte: Lapin Polyclonal unconjugated

anti-Activin A Receptor Type II-Like 1 (ACVRL1) (AA 22-119) antibody
ACVRL1 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 5B1 unconjugated

anti-Activin A Receptor Type II-Like 1 (ACVRL1) (AA 22-119) antibody
ACVRL1 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 2C12 unconjugated

Indications d'application

WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

4 °C,-20 °C

Stockage commentaire

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption

6 months
Muñoz-Félix, Cuesta, Perretta-Tejedor, Subileau, López-Hernández, López-Novoa, Martínez-Salgado: "Identification of bone morphogenetic protein 9 (BMP9) as a novel profibrotic factor in vitro." dans: Cellular signalling, Vol. 28, Issue 9, pp. 1252-61, (2017) (PubMed).

Antonov, Antonova, Fujii, ten Dijke, Handa, Catravas, Verin: "Regulation of endothelial barrier function by TGF-? type I receptor ALK5: potential role of contractile mechanisms and heat shock protein 90." dans: Journal of cellular physiology, Vol. 227, Issue 2, pp. 759-71, (2011) (PubMed).

Finnson, Parker, ten Dijke, Thorikay, Philip: "ALK1 opposes ALK5/Smad3 signaling and expression of extracellular matrix components in human chondrocytes." dans: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 23, Issue 6, pp. 896-906, (2008) (PubMed).

Yu, Pisitkun, Wang, Shen, Knepper: "LC-MS/MS analysis of apical and basolateral plasma membranes of rat renal collecting duct cells." dans: Molecular & cellular proteomics : MCP, Vol. 5, Issue 11, pp. 2131-45, (2006) (PubMed).
Antigène

ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))

Autre désignation

ACVRL1

Sujet

ACVRL1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. This protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.

Poids moléculaire

56124

ID gène

94

NCBI Accession

NP_000011, NP_001070869

UniProt

P37023