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ADAMTS4 anticorps (C-Term)

Cet anticorps Lapin Polyclonal détecte spécifiquement ADAMTS4 dans WB. Il présente une réactivité avec des échantillons de Humain et Souris.Il a été cité dans 1 publication.
N° du produit ABIN391642
434,77 €
Plus frais de livraison 40,00 € et TVA
Destination: France
Envoi sous 14 à 17 jours ouvrables

Aperçu rapide pour ADAMTS4 anticorps (C-Term) (ABIN391642)

Antigène

Voir toutes ADAMTS4 Anticorps
ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))

Reactivité

  • 76
  • 48
  • 21
  • 7
  • 6
  • 6
  • 5
  • 4
  • 3
  • 3
  • 3
  • 1
  • 1
Humain, Souris

Hôte

  • 65
  • 13
  • 4
Lapin

Clonalité

  • 70
  • 12
Polyclonal

Conjugué

  • 39
  • 10
  • 7
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp ADAMTS4 est non-conjugé

Application

  • 61
  • 25
  • 15
  • 13
  • 13
  • 11
  • 7
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)

Clone

RB18037
  • Épitope

    • 15
    • 7
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 705-736, C-Term

    Homologie

    H

    Purification

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogène

    This ADAMTS4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 705-736 amino acids from the C-terminal region of human ADAMTS4.

    Isotype

    Ig Fraction
  • Indications d'application

    WB: 1:1000. WB: 1:2000. WB: 1:1000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Date de péremption

    6 months
  • Lee, Lee, Gil, Kim, Lee, Kim, Park: "Differential expression patterns of a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) -1, -4, -5, and -14 in human placenta and gestational trophoblastic diseases." dans: Archives of pathology & laboratory medicine, Vol. 138, Issue 5, pp. 643-50, (2014) (PubMed).

  • Antigène

    ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))

    Autre désignation

    ADAMTS4

    Sujet

    ADAMTS4 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma.

    Poids moléculaire

    90197

    ID gène

    9507

    NCBI Accession

    NP_005090

    UniProt

    O75173
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