Iba1 anticorps
Aperçu rapide pour Iba1 anticorps (ABIN498378)
Antigène
Voir toutes Iba1 (IBA1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- This antibody detects endogenous levels of AIF-M1 protein. (region surrounding Tyr85)
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Réactivité croisée (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
Purification
- Affinity chromatography
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Pureté
- > 95 % by SDS-PAGE
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anti-Ionized Calcium-binding Adapter Molecule 1 (IBA1) (C-Term) antibody
IBA1 Reactivité: Humain WB, IHC, ICC, IF, IHC (p), FACS, IHC (fro), IHC (ff) Hôte: Lapin Polyclonal unconjugated
anti-Ionized Calcium-binding Adapter Molecule 1 (IBA1) (AA 51-147) antibodyIBA1 Reactivité: Humain, Rat, Souris WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Ionized Calcium-binding Adapter Molecule 1 (IBA1) antibodyIBA1 Reactivité: Humain WB, IHC, ICC, IP, IF, IHC (p), FACS, IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Ionized Calcium-binding Adapter Molecule 1 (IBA1) (AA 1-147) antibodyIBA1 Reactivité: Rat WB, IHC, ICC, IP Hôte: Lapin Polyclonal unconjugated
anti-Ionized Calcium-binding Adapter Molecule 1 (IBA1) (AA 1-147) antibodyIBA1 Reactivité: Rat WB Hôte: Souris Monoclonal C5 unconjugated
anti-Ionized Calcium-binding Adapter Molecule 1 (IBA1) (Internal Region) antibodyVerified IBA1 Reactivité: Humain IHC, ELISA, IF, FACS Hôte: Chèvre Polyclonal unconjugated
anti-Ionized Calcium-binding Adapter Molecule 1 (IBA1) (C-Term) antibodyVerified IBA1 Reactivité: Humain, Rat, Souris WB, IHC, ELISA Hôte: Chèvre Polyclonal unconjugated
anti-Ionized Calcium-binding Adapter Molecule 1 (IBA1) (AA 1-147) antibodyIBA1 Reactivité: Humain WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Ionized Calcium-binding Adapter Molecule 1 (IBA1) (AA 35-102) antibodyIBA1 Reactivité: Souris WB, IHC, ICC, IP Hôte: Lapin Polyclonal unconjugated
anti-Ionized Calcium-binding Adapter Molecule 1 (IBA1) (AA 1-146) antibodyIBA1 Reactivité: Humain IHC Hôte: Souris Monoclonal AIF1-1909 unconjugated
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Indications d'application
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1,0 mg/mL
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Buffer
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))
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Autre désignation
- AIF1
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Sujet
- Apoptosis is characterized by several morphological nuclear changes including chromatin condensation and nuclear fragmentation. These changes are triggered by the activation of members of caspase family, caspase activated DNase, and several novel proteins. A novel gene, the product of which causes chromatin condensation and DNA fragmentation, was recently identified, cloned, and designated apoptosis inducing factor (AIF). Like the critical molecules, cytochrome c and caspase 9, in apoptosis, AIF localizes in mitochondria. AIF translocates to the nucleus when apoptosis is induced and induces mitochondria to release the apoptogenic proteins cytochrome c and caspase 9. AIF induces chromatin condensation and large scale DNA fragmentation, which are the hallmarks of apoptosis, of the isolated nucleus and the nucleus in live cells by microinjection and apoptosis stimuli. AIF is highly conserved between human and mouse and widely expressed.Synonyms: AIF-1, Allograft inflammatory factor 1, IBA1, Ionized Calcium-Binding Adapter Molecule 1, Protein G1
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Poids moléculaire
- approx. 67 kDa
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ID gène
- 199
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NCBI Accession
- NP_001614
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UniProt
- P55008
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Pathways
- Smooth Muscle Cell Migration
Antigène
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