ATG5 anticorps
(1 reference)Aperçu rapide pour ATG5 anticorps (ABIN650657)
Antigène
Voir toutes ATG5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Purification
- This antibody is purified through a protein A column, followed by dialysis against PBS.
-
Immunogène
- This ATG5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the full length of human ATG5.
-
Isotype
- Ig Fraction
-
-
anti-ATG5 Autophagy Related 5 (ATG5) (AA 209-238), (C-Term) antibody
ATG5 Reactivité: Humain, Souris WB, IF, IHC (p) Hôte: Lapin Polyclonal RB7547 unconjugated
anti-ATG5 Autophagy Related 5 (ATG5) (AA 101-200) antibodyATG5 Reactivité: Humain, Souris, Rat WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-ATG5 Autophagy Related 5 (ATG5) (AA 1-275) antibodyATG5 Reactivité: Humain WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-ATG5 Autophagy Related 5 (ATG5) (AA 144-275) antibodyATG5 Reactivité: Humain ELISA, ICC, FACS Hôte: Souris Monoclonal 3C7A8 unconjugated
anti-ATG5 Autophagy Related 5 (ATG5) (AA 176-275) antibodyATG5 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 1G11 unconjugated
anti-ATG5 Autophagy Related 5 (ATG5) (AA 1-119) antibodyATG5 Reactivité: Humain WB, IHC, ELISA Hôte: Souris Monoclonal ATG5-2101 unconjugated
anti-ATG5 Autophagy Related 5 (ATG5) (AA 1-30), (N-Term) antibodyATG5 Reactivité: Humain WB, IF, IHC (p) Hôte: Lapin Polyclonal RB7466 unconjugated
anti-ATG5 Autophagy Related 5 (ATG5) (AA 1-30), (N-Term) antibodyATG5 Reactivité: Humain, Souris WB, IF, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
anti-ATG5 Autophagy Related 5 (ATG5) (AA 1-30) antibodyATG5 Reactivité: Humain, Souris WB, IHC, ELISA, IF Hôte: Lapin Polyclonal unconjugated
anti-ATG5 Autophagy Related 5 (ATG5) (C-Term) antibodyATG5 Reactivité: Humain, Souris, Rat WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated
-
-
Indications d'application
- IF: 1:200. WB: 1:1000. WB: 1:500. WB: 1:500. IHC-P: 1:10~50
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
Date de péremption
- 6 months
-
-
-
: "Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 6, pp. 2003-8, (2012) (PubMed).
-
-
- ATG5 (ATG5 Autophagy Related 5 (ATG5))
-
Autre désignation
- APG5
-
Sujet
- Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG5, required for autophagy, conjugates to ATG12 and associates with an isolation membrane to form a cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. APG5 may also play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.
-
Poids moléculaire
- 32447
-
ID gène
- 9474
-
NCBI Accession
- NP_004840
-
UniProt
- Q9H1Y0
-
Pathways
- Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagy
Antigène
-
