ATG5 anticorps (AA 1-275)

N° du produit ABIN3020674

Détail du produit anti-ATG5 anticorps

Antigène: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Épitope: AA 1-275

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: MTDDKDVLRD VWFGRIPTCF TLYQDEITER EAEPYYLLLP RVSYLTLVTD KVKKHFQKVM RQEDISEIWF EYEGTPLKWH YPIGLLFDLL ASSSALPWNI TVHFKSFPEK DLLHCPSKDA IEAHFMSCMK EADALKHKSQ VINEMQKKDH KQLWMGLQND RFDQFWAINR KLMEYPAEEN GFRYIPFRIY QTTTERPFIQ KLFRPVAADG QLHTLGDLLK EVCPSAIDPE DGEKKNQVMI HGIEPMLETP LQWLSEHLSY PDNFLHISII PQPTD

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-275 of human ATG5 (NP_004840.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-ATG5 (ABIN3020674)

Chen, Wu, Sang, Wang, Zong, Sun, Liu, Zhao: "The lncRNA HULC functions as an oncogene by targeting ATG7 and ITGB1 in epithelial ovarian carcinoma." dans: Cell death & disease, Vol. 8, Issue 10, pp. e3118, (2018) (PubMed).

Li, Zhao, Wang, Shao, Wang, Wang, Xing: "Regulation of autophagy factors by oxidative stress and cardiac enzymes imbalance during arsenic or/and copper induced cardiotoxicity in Gallus gallus." dans: Ecotoxicology and environmental safety, Vol. 148, pp. 125-134, (2018) (PubMed).

Sun, Li, Zhao, Wang, Liu, Shao, Xue, Xing: "Synergistic effect of copper and arsenic upon oxidative stress, inflammation and autophagy alterations in brain tissues of Gallus gallus." dans: Journal of inorganic biochemistry, Vol. 178, pp. 54-62, (2018) (PubMed).

Shao, Zhao, Wang, Liu, Zong, Xing: "Copper-Mediated Mitochondrial Fission/Fusion Is Associated with Intrinsic Apoptosis and Autophagy in the Testis Tissues of Chicken." dans: Biological trace element research, (2018) (PubMed).

Shao, Zhao, Wang, Liu, Li, Luo, Xing: "The apoptosis in arsenic-induced oxidative stress is associated with autophagy in the testis tissues of chicken." dans: Poultry science, Vol. 97, Issue 9, pp. 3248-3257, (2018) (PubMed).

Gou, Zhao, Fan, Yuan, Liao, He, Xu, Chen: "Autophagy induces apoptosis and death of T lymphocytes in the spleen of pigs infected with CSFV." dans: Scientific reports, Vol. 7, Issue 1, pp. 13577, (2017) (PubMed).

Détails sur ATG5

Antigène: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Autre désignation: ATG5 (ATG5 Produits)

Synonymes: anticorps APG5, anticorps APG5-LIKE, anticorps APG5L, anticorps ASP, anticorps hAPG5, anticorps ATG5, anticorps CG1643, anticorps DmAtg5, anticorps Dmel\\CG1643, anticorps atg5, anticorps 2010107M05Rik, anticorps 3110067M24Rik, anticorps AW319544, anticorps Apg5l, anticorps Atg5l, anticorps C88337, anticorps Paddy, anticorps apg5l, anticorps zgc:100934, anticorps ATATG5, anticorps AUTOPHAGY 5, anticorps MKP11.20, anticorps MKP11_20, anticorps autophagy related 5, anticorps Autophagy-related 5, anticorps ATG5 autophagy related 5 homolog (S. cerevisiae), anticorps autophagy related 5 L homeolog, anticorps similar to S. cerevisiae ATG5 (YPL149W) which nucleates preautophagosome formation as a conjugate with Atg12, anticorps autophagy protein Apg5 family, anticorps ATG5, anticorps Atg5, anticorps atg5, anticorps atg5.L, anticorps APG5

Sujet: The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene.,ATG5,APG5,APG5-LIKE,APG5L,ASP,hAPG5,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Autophagy,Ubiquitin,Endocrine & Metabolism,Mitochondrial metabolism,Immunology & Inflammation,Cardiovascular,Heart,ATGs,ATG5

Poids moléculaire: 22 kDa/32 kDa

ID gène: 9474

UniProt: Q9H1Y0

Pathways: Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagy