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ATG4B anticorps (N-Term)

Cité dans 2 publications. Cet anticorps anti-ATG4B Polyclonal Lapin (Clone RB7496) (ABIN388494) détecte spécifiquement ATG4B dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain et Souris.

Western blot analysis of anti-hG4B-R31 Pab 1809a in 293 cell line lysates transiently transfected with the ATG4B gene (2 μg/lane). (ATG4B anticorps (N-Term))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (ATG4B anticorps (N-Term))

IHC (p)

The anti-G4B Pab 1809a is used in Western blot to detect G4B in CEM tissue lysate (ATG4B anticorps (N-Term))

G4B Antibody (R31) 1809a western blot analysis in mouse cerebellum tissue lysates (35 μg/lane). (ATG4B anticorps (N-Term))

4 images

(2 références)

N° du produit ABIN388494

434,77 €

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Aperçu rapide pour ATG4B anticorps (N-Term) (ABIN388494)

Antigène

Voir toutes ATG4B Anticorps

ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Reactivité

Humain, Souris

Hôte

Lapin

Clonalité

Polyclonal

Conjugué

Cet anticorp ATG4B est non-conjugé

Application

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

RB7496

Discover our top product ATG4B Anticorps primaire

Épitope
15

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AA 16-45, N-Term

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène

This ATG4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-45 amino acids from the N-terminal region of human ATG4B.

Isotype

Ig Fraction
anti-Autophagy related 4B Cysteine Peptidase (ATG4B) (AA 1-221) antibody
ATG4B Reactivité: Humain, Souris WB, ELISA, FACS Hôte: Souris Monoclonal 6C3C5 unconjugated

anti-Autophagy related 4B Cysteine Peptidase (ATG4B) (AA 1-221) antibody
ATG4B Reactivité: Humain WB, ELISA, IHC, FACS Hôte: Souris Monoclonal 4H9A5 unconjugated

anti-Autophagy related 4B Cysteine Peptidase (ATG4B) (AA 358-390), (C-Term) antibody
ATG4B Reactivité: Humain WB, IF, IHC (p) Hôte: Lapin Polyclonal RB7560 unconjugated

anti-Autophagy related 4B Cysteine Peptidase (ATG4B) (AA 350-400) antibody
ATG4B Reactivité: Humain WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated

anti-Autophagy related 4B Cysteine Peptidase (ATG4B) antibody
KD Validated ATG4B Reactivité: Humain WB, FACS Hôte: Lapin Monoclonal 23GB3240 unconjugated Recombinant Antibody

anti-Autophagy related 4B Cysteine Peptidase (ATG4B) (AA 85-200) antibody
ATG4B Reactivité: Humain, Souris, Rat ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) Hôte: Lapin Polyclonal unconjugated

anti-Autophagy related 4B Cysteine Peptidase (ATG4B) (AA 23-53), (N-Term) antibody
ATG4B Reactivité: Humain, Souris WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated

anti-Autophagy related 4B Cysteine Peptidase (ATG4B) antibody
ATG4B Reactivité: Humain WB, IHC, IHC (p) Hôte: Souris Monoclonal unconjugated

anti-Autophagy related 4B Cysteine Peptidase (ATG4B) antibody
ATG4B Reactivité: Humain WB, IF Hôte: Lapin Monoclonal unconjugated

anti-Autophagy related 4B Cysteine Peptidase (ATG4B) (C-Term) antibody
ATG4B Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Chien, Cobaye, Lapin, Singe, Cheval, Roussette (Chauve-souris), Porc WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated

Indications d'application

WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

4 °C,-20 °C

Stockage commentaire

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption

6 months
Yang, Zhao, Mei, Jiang, Geng, Li, Yao, Liu, Kong, Cao: "HMGA2 plays an important role in Cr (VI)-induced autophagy." dans: International journal of cancer, Vol. 141, Issue 5, pp. 986-997, (2017) (PubMed).

Garneau, Alvarez, Paquin, Lussier, Rancourt, Tremblay, Beaulieu, Rivard: "Nuclear expression of E2F4 induces cell death via multiple pathways in normal human intestinal epithelial crypt cells but not in colon cancer cells." dans: American journal of physiology. Gastrointestinal and liver physiology, Vol. 293, Issue 4, pp. G758-72, (2007) (PubMed).
Antigène

ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Autre désignation

ATG4B

Sujet

Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG4 is a cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.

Poids moléculaire

44294

ID gène

23192

NCBI Accession

NP_037457, NP_847896

UniProt

Q9Y4P1

Pathways

Autophagy