CCR7 anticorps (C-Term)
Aperçu rapide pour CCR7 anticorps (C-Term) (ABIN122618)
Antigène
Voir toutes CCR7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Specificité
- Reacts with Humna CC Chemokine Receptor 7 (CCR7) (family: GPCR, subfamily: Chemokine). BLAST analysis of the peptide immunogen showed no homology with other Human proteins.
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Purification
- Immunoaffinity Chromatography
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Immunogène
- Synthetic peptide - KLH conjugated
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anti-Chemokine (C-C Motif) Receptor 7 (CCR7) (AA 25-59) antibody
CCR7 Reactivité: Humain, Souris, Rat, Mouton WB, FACS, ELISA, ICC, IHC (p), IF (p), IF (cc), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 7 (CCR7) (AA 11-37), (N-Term) antibodyCCR7 Reactivité: Humain, Souris WB, FACS, IF, IHC (p) Hôte: Lapin Polyclonal RB21736 unconjugated
anti-Chemokine (C-C Motif) Receptor 7 (CCR7) antibodyCCR7 Reactivité: Humain WB, FACS, ELISA Hôte: Souris Monoclonal 4B7B8 unconjugated
anti-Chemokine (C-C Motif) Receptor 7 (CCR7) antibodyCCR7 Reactivité: Humain WB, IHC, IF Hôte: Lapin Monoclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 7 (CCR7) (AA 11-37) antibodyCCR7 Reactivité: Humain, Souris WB, FACS, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 7 (CCR7) (AA 1-100) antibodyCCR7 Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 7 (CCR7) (AA 332-378) antibodyCCR7 Reactivité: Humain ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 7 (CCR7) (C-Term) antibodyCCR7 Reactivité: Humain, Singe, Boeuf (Vache), Roussette (Chauve-souris), Cheval IHC, ICC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 7 (CCR7) antibodyCCR7 Reactivité: Humain WB, FACS, ICC Hôte: Lapin Monoclonal 23GB6485 unconjugated Recombinant Antibody
anti-Chemokine (C-C Motif) Receptor 7 (CCR7) (AA 26-40), (Extracellular) antibodyCCR7 Reactivité: Humain WB, FACS, IHC, LCI Hôte: Lapin Polyclonal unconjugated
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Indications d'application
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Immunohistochemistry with formalin fixed paraffin embedded tissues: 6-8 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS, 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C forlonger. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Date de péremption
- 12 months
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- CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))
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Autre désignation
- CD197 / CCR7
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Sujet
- CCR7, a Chemokine Receptor, is involved in lymphocyte recirculation through secondary lymphoid organs and moving lymphocytes and dendritic cells into distinct tissue compartments. CCR7 is called the Epstein-Barr-induced receptor because it mediates Epstein-Barr viral effects on B lymphocytes. CCR7 expression is up-regulated in mature dendritic cells, B cells infected with EBV, and in CD4+ cells infected with human herpes virus 6 and 7. Immature dendritic cells have been shown to express chemokine receptor 5 (CCR5) and migrate in response to macrophage inflammatory protein-1alpha (MIP-1alpha), whereas mature dendritic cells switch to CCR7 expression and respond exclusively to MIP-3beta and 6Ckine. Maturing dendritic cells upregulate CCR7, which drives their migration to the T-cell areas of the draining lymph nodes where antigen is presented to naive T cells. CCR7 has been reported to be expressed in blood, bone marrow, lymph node, and intestine. This receptor is particularly expressed in lymphoid tissues and in activated B and T lymphocytes. ESTs have been isolated from blood, embryo, lymph node, and thymus librariesSynonyms: BLR2, C-C CKR-7, C-C chemokine receptor type 7, CC-CKR-7, CCR-7, CMKBR7, EBI1, EBV-induced G-protein coupled receptor 1, EVI1, MIP-3 beta receptor
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ID gène
- 1236
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UniProt
- P32248
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Pathways
- Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process
Antigène
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