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CCR8 anticorps (Extracellular Loop)

L’anticorps anti-CCR8 Polyclonal Lapin est utilisé pour la détection de CCR8 dans des échantillons de Humain. Il a été validé pour WB.
N° du produit ABIN265001
1.045,54 €
Plus frais de livraison 40,00 € et TVA
0.1 mg
Destination: France
Envoi sous 17 jours ouvrables

Aperçu rapide pour CCR8 anticorps (Extracellular Loop) (ABIN265001)

Antigène

Voir toutes CCR8 Anticorps
CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Reactivité

  • 75
  • 21
  • 14
  • 2
  • 2
  • 1
  • 1
Humain

Hôte

  • 54
  • 9
  • 7
  • 4
  • 4
  • 3
Lapin

Clonalité

  • 47
  • 34
Polyclonal

Conjugué

  • 50
  • 6
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Cet anticorp CCR8 est non-conjugé

Application

  • 48
  • 35
  • 33
  • 14
  • 13
  • 13
  • 7
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Épitope

    • 11
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 183-201, Extracellular Loop

    Specificité

    This antibody reacts to CCR8.

    Purification

    Purified

    Immunogène

    Antibody raised against a synthetic peptide corresponding to amino acids 183 to 201 of the human CCR8. Peptide sequence is located in the second extracellular loop.

    Isotype

    IgG
  • Indications d'application

    Western Blot: 0.5 to 1 μg/mL. Detects an approximately 50 kDa band in human spleentissue lysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Buffer

    Phosphate buffered saline solution containing 0.02 % sodium azide as a preservative

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    DO NOT FREEZE!

    Stock

    4 °C

    Stockage commentaire

    The antibody can be shipped at ambient temperature. Store (in aliquots) at 2-8 °C.
  • Antigène

    CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

    Autre désignation

    CDw198 / CCR8

    Sujet

    CCR8 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human and murine CCR8 were cloned and designated TER1, CKR-L1, and ChemR11-4. The encoded seven transmembrane protein was identified as the receptor for human CC chemokine I-309 and renamed CCR8. Recently, CCR8 was found to serve as a coreceptor for diverse T-cell tropic, dual-tropic and macrophage-tropic HIV-1 strains5. CCR8 mediates CC chemokine I-309 induced monocyte chemoattraction and HIV-1 envelope fusion and virus infection, which can be prevented by the CCR8 ligand I-309. CCR8 is expressed in spleen, thymus and T lymphoblastic cell lines.Synonyms: C-C CKR-8, C-C chemokine receptor type 8, CC-CKR-8, CC-chemokine receptor CHEMR1, CCR-8, CKRL1, CMKBR8, CMKBRL2, Chemokine receptor-like 1, GPR-CY6, TER1

    ID gène

    1237

    NCBI Accession

    NP_005192

    UniProt

    P51685
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