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CCR8 anticorps (AA 183-201)

L’anticorps anti-CCR8 Polyclonal Lapin est utilisé pour la détection de CCR8 dans des échantillons de Humain. Il a été validé pour WB.
N° du produit ABIN319016
809,23 €
Plus frais de livraison 40,00 € et TVA
0.1 mg
Destination: France
Envoi sous 17 jours ouvrables

Aperçu rapide pour CCR8 anticorps (AA 183-201) (ABIN319016)

Antigène

Voir toutes CCR8 Anticorps
CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Reactivité

  • 76
  • 21
  • 14
  • 2
  • 2
  • 1
  • 1
Humain

Hôte

  • 55
  • 9
  • 7
  • 4
  • 4
  • 3
Lapin

Clonalité

  • 48
  • 34
Polyclonal

Conjugué

  • 51
  • 6
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Cet anticorp CCR8 est non-conjugé

Application

  • 49
  • 35
  • 33
  • 14
  • 13
  • 13
  • 7
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Épitope

    • 11
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 183-201

    Specificité

    This antibody recognises the chemokine receptor CCR8, also known as CDw198, which has been identified as a co-receptor for HIV infection. CCR8 is a receptor for the human chemokine 1-309 which is expressed on spleen, thymus and T lymphoblastic cell lines. This antibody detects a band of approximately 50 kDa.

    Purification

    Purified

    Immunogène

    Peptide corresponding to amino acids 183 to 201 of human CDw198 (CCR8).

    Isotype

    IgG
  • Indications d'application

    Western Blot: 1: 500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    0.5 mg/mL

    Buffer

    Phosphate buffered saline containing 0.02 % Sodium Azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène

    CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

    Autre désignation

    CDw198 / CCR8

    Sujet

    CCR8 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation regulated cytokine (TARC) and macrophage inflammatory protein 1 beta (MIP1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. CCR8 expression has been reported in spleen and thymus, natural killer cells, monocytes, and T cells, and at lower levels in peripheral blood leukocytes. CCR8 is also believed to be alternative coreceptor with CD4 for HIV-1 infection.Synonyms: C-C CKR-8, C-C chemokine receptor type 8, CC-CKR-8, CC-chemokine receptor CHEMR1, CCR-8, CKRL1, CMKBR8, CMKBRL2, Chemokine receptor-like 1, GPR-CY6, TER1

    ID gène

    1237

    NCBI Accession

    NP_005192

    UniProt

    P51685
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