PLEKHO1 anticorps (AA 51-170)
Aperçu rapide pour PLEKHO1 anticorps (AA 51-170) (ABIN675039)
Antigène
Voir toutes PLEKHO1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 51-170
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Réactivité croisée
- Humain, Souris
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Homologie
- Rat
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human CKIP-1
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Isotype
- IgG
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anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) antibody
PLEKHO1 Reactivité: Humain, Souris, Rat ELISA, WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) (AA 1-409) antibodyPLEKHO1 Reactivité: Humain WB, IF Hôte: Souris Polyclonal unconjugated
anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) (AA 49-77), (N-Term) antibodyPLEKHO1 Reactivité: Humain WB, FACS, IHC (p) Hôte: Lapin Polyclonal RB19797 unconjugated
anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) (AA 1-409) antibodyPLEKHO1 Reactivité: Humain ELISA, WB Hôte: Souris Monoclonal 3D5 unconjugated
anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) (AA 1-409) antibodyPLEKHO1 Reactivité: Humain ELISA, IHC (p) Hôte: Souris Monoclonal 1C7 unconjugated
anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) (AA 143-404) antibodyPLEKHO1 Reactivité: Humain ELISA, IF Hôte: Lapin Polyclonal unconjugated
anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) (AA 1-410) antibodyPLEKHO1 Reactivité: Humain ELISA, IHC, IHC (p) Hôte: Souris Monoclonal 1C7 unconjugated
anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) (N-Term) antibodyPLEKHO1 Reactivité: Humain, Singe WB Hôte: Lapin Polyclonal unconjugated
anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) (N-Term) antibodyPLEKHO1 Reactivité: Humain, Rat, Boeuf (Vache), Porc WB Hôte: Lapin Polyclonal unconjugated
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Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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- PLEKHO1 (Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1))
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Autre désignation
- CKIP-1
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Sujet
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Synonyms: Pleckstrin homology domain-containing family O member 1, PH domain-containing family O member 1, C-Jun-binding protein, JBP, Casein kinase 2-interacting protein 1, CK2-interacting protein 1, CKIP-1, Osteoclast maturation-associated gene 120 protein, PLEKHO1, CKIP1, OC120, HQ0024C
Background: Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP). May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2). Appears to target ATM to the plasma membrane. Appears to also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival. Also implicated in PI3K-regulated muscle differentiation, the regulation of AP-1 activity (plasma membrane bound AP-1 regulator that translocates to the nucleus) and the promotion of apoptosis induced by tumor necrosis factor TNF. When bound to PKB, it inhibits it probably by decreasing PKB level of phosphorylation.
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ID gène
- 51177
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UniProt
- Q53GL0
Antigène
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