GGA3 anticorps (AA 400-425)
Aperçu rapide pour GGA3 anticorps (AA 400-425) (ABIN129660)
Antigène
Voir toutes GGA3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 400-425
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N° du produit (Fournisseur)
- 600-401-893
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Fournisseur
- Rockland
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Fonction
- GGA3 Antibody
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Réactivité croisée (Details)
- This affinity purified antibody is directed against human GGA3 protein.
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Attributs du produit
- Synonyms: rabbit anti-GGA3 antibody, GGA-3, GGA 3, ADP-ribosylation factor-binding protein GGA3, Golgi-localized gamma ear-containing ARF-binding protein 3
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Purification
- The product was affinity purified from monospecific antiserum by immunoaffinity purification.
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Stérilité
- Sterile filtered
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Immunogène
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Immunogen: This affinity-purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near amino acids 400-425 of Human GGA3.
Immunogen Type: Conjugated Peptide
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Isotype
- IgG
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anti-Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 3 (GGA3) (C-Term) antibody
GGA3 Reactivité: Humain WB, IHC (p), IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 3 (GGA3) (AA 424-542) antibodyGGA3 Reactivité: Humain WB, IF Hôte: Souris Monoclonal 8-GGA3 unconjugated
anti-Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 3 (GGA3) (N-Term) antibodyGGA3 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
anti-Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 3 (GGA3) (C-Term) antibodyVerified GGA3 Reactivité: Humain ELISA, IHC Hôte: Chèvre Polyclonal unconjugated
anti-Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 3 (GGA3) (AA 342-503) antibodyGGA3 Reactivité: Humain ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 3 (GGA3) (AA 179-228) antibodyGGA3 Reactivité: Humain, Souris, Cheval, Boeuf (Vache), Chien, Cobaye, Poisson zèbre (Danio rerio), Singe, Porc, Roussette (Chauve-souris), Poulet, Xenopus laevis WB Hôte: Lapin Polyclonal unconjugated
anti-Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 3 (GGA3) (AA 7-535) antibodyGGA3 Reactivité: Humain WB, ELISA, IHC, IF, ICC, FACS Hôte: Lapin Polyclonal unconjugated
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Indications d'application
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Application Note: This affinity purified antibody has been tested for use in ELISA and western blot. Specific conditions for reactivity should be optimized by the end user. Expect bands at 78 kDa in size corresponding to GGA3 by western blotting in the appropriate cell lysate or extract.
Western Blot Dilution: 1:500 - 1:3,000
Immunoprecipitation Dilution: 1:100
ELISA Dilution: 1:10,000 - 1:50,000
Other: User Optimized
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.48 mg/mL
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Buffer
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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Date de péremption
- 12 months
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- GGA3 (Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 3 (GGA3))
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Autre désignation
- GGA3
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Sujet
- Background: GGA3 (also known as ADP-ribosylation factor binding protein GGA3, Golgi-localized, gamma ear-containing, ARF-binding protein 3, Gamma-adaptin related protein 3) plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. This protein mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif. GGA1 is a monomeric protein that interacts with SORT1, SORL1, LRP3, GGA binding partner (GGABP) and P200, GGA1 and GGA2 as well as RABEP1, RABGEF1 and type-I membrane proteins M6PR/CD-MPR, IGF2R/CI-MPR and BACE1. GGA3 is a ubiquitously expressed membrane-associated protein that is localized to TGN and endosomes. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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ID gène
- 23163, 20336267
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UniProt
- Q9NZ52
Antigène
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