HRK anticorps (Middle Region)
Aperçu rapide pour HRK anticorps (Middle Region) (ABIN318751)
Antigène
Voir toutes HRK AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Specificité
- This antibody detects Harakiri (HRK), also known as DP5.
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Purification
- Purified
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Immunogène
- 15 amino acid peptide from near the centre of human HRK (NP_003797).
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Isotype
- IgG
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anti-Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK) antibody
HRK Reactivité: Humain ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK) (Center) antibodyHRK Reactivité: Humain, Souris, Rat WB Hôte: Lapin Polyclonal unconjugated
anti-Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK) (AA 15-50) antibodyHRK Reactivité: Humain, Souris WB, IHC (p) Hôte: Lapin Polyclonal RB04688 unconjugated
anti-Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK) (AA 1-50) antibodyHRK Reactivité: Souris, Rat ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC Hôte: Lapin Polyclonal unconjugated
anti-Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK) (N-Term) antibodyHRK Reactivité: Humain, Boeuf (Vache), Chien, Lapin, Porc WB Hôte: Lapin Polyclonal unconjugated
anti-Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK) (N-Term) antibodyHRK Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin WB Hôte: Lapin Polyclonal unconjugated
anti-Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK) (BH3 Domain) antibodyHRK Reactivité: Humain, Souris WB, IHC Hôte: Lapin Polyclonal unconjugated
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Indications d'application
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Western Blot: 2 - 5g/mL, detects a band of approximately 13 kDa in mouse pancreas tissuelysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Précaution d'utilisation
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- HRK (Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK))
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Autre désignation
- Harakiri / HRK
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Sujet
- HRK is a BH3 only protein of the Bcl-2 family, which promotes Bax dependent apoptosis. HRK regulates apoptosis through its interaction with the anti-apoptotic proteins Bcl-2 and Bcl-XL, and in conjunction to the mitochondrial pore forming protein p32. HRK is thought to have a specific role in initiating neuronal and haematopoietic cell apoptosis, in particular to growth factor deprivation. Aberrant methylation of HRK is frequently detected in primary colorectal cancers. Despite its predicted molecular weight, HRK often migrates at 12-15kD.Synonyms: Activator of apoptosis harakiri, BH3-interacting domain-containing protein 3, BID3, Neuronal death protein DP5
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ID gène
- 8739
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NCBI Accession
- NP_003797
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UniProt
- O00198
Antigène
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