HSP90AA1 anticorps (AA 289-300)
Aperçu rapide pour HSP90AA1 anticorps (AA 289-300) (ABIN129685)
Antigène
Voir toutes HSP90AA1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 289-300
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N° du produit (Fournisseur)
- 600-401-929
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Fournisseur
- Rockland
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Fonction
- HSP90 alpha Antibody
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Réactivité croisée (Details)
- This affinity-purified antibody is directed against human Hsp90 protein.
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Attributs du produit
- Synonyms: rabbit anti-Heat Shock Protein HSP 90-alpha antibody, HSP 86 antibody, Heat shock 86 kDa antibody, Renal carcinoma antigen NY REN 38 antibody, Heat shock 90 kDa protein 1 alpha antibody, Lipopolysaccharide-associated protein 2, LAP-2, HSP90A, HSPC1, HSPCA, HSP90AA1, HSP 90-α
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Purification
- The product was affinity purified from monospecific antiserum by immunoaffinity purification.
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Stérilité
- Sterile filtered
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Immunogène
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Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 289-300 of human Hsp90 protein.
Immunogen Type: Conjugated Peptide
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Isotype
- IgG
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anti-Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 1 (HSP90AA1) antibody
HSP90AA1 Reactivité: Humain, Souris, Singe WB, IHC, ELISA, FACS Hôte: Souris Monoclonal 5G5 unconjugated
anti-Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 1 (HSP90AA1) (AA 229-263) antibodyHSP90AA1 Reactivité: Poisson zèbre (Danio rerio) WB, IHC (p) Hôte: Lapin Polyclonal RB47443 unconjugated
anti-Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 1 (HSP90AA1) (AA 698-732) antibodyHSP90AA1 Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 1 (HSP90AA1) (AA 433-732) antibodyHSP90AA1 Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated
anti-Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 1 (HSP90AA1) antibodyHSP90AA1 Reactivité: Humain, Souris, Rat WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 1 (HSP90AA1) (AA 2-365) antibodyHSP90AA1 Reactivité: Humain, Souris, Rat WB, IHC, IF, ICC, FACS Hôte: Lapin Polyclonal unconjugated
anti-Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 1 (HSP90AA1) (AA 454-488), (C-Term) antibodyHSP90AA1 Reactivité: Humain, Souris, Rat, Singe WB, IHC, IF, ICC, FACS Hôte: Lapin Polyclonal unconjugated
anti-Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 1 (HSP90AA1) antibodyHSP90AA1 Reactivité: Humain WB, IHC, ELISA, IF, IP Hôte: Lapin Monoclonal 4B5 unconjugated Recombinant Antibody
anti-Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 1 (HSP90AA1) (C-Term) antibodyHSP90AA1 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 1 (HSP90AA1) antibodyHSP90AA1 Reactivité: Humain WB, ELISA, IP, FACS Hôte: Lapin Monoclonal 10D6 unconjugated Recombinant Antibody
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Indications d'application
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Immunohistochemistry Dilution: User Optimized
Application Note: This affinity purified antibody has been tested for use in ELISA and western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 90 kDa in size corresponding to Hsp90 protein by western blotting in the appropriate cell lysate or extract.
Western Blot Dilution: 1:500 - 1:2,500
ELISA Dilution: 1:5,000 - 1:25,000
Other: User Optimized
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.24 mg/mL
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Buffer
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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Date de péremption
- 12 months
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- HSP90AA1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 1 (HSP90AA1))
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Autre désignation
- HSP90AA1
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Sujet
- Background: This antibody is designed, produced, and validated as part of a collaboration with the National Cancer Institute (NCI) and is suitable for Cancer, Immunology and Nuclear Signaling research. Hsp90 is a member of the heat shock protein 90 family that functions as a molecular chaperone and has ATPase activity. Hsp90 family proteins are highly conserved between isoforms and species. Several signal transduction pathways depend on Hsp90 function including erbB2, steroid hormone receptors (such as androgen, progesterone, glucocorticoid, and aryl-hydrocarbon), and hypoxia sensing (Hif1alpha). Recent reports show that tumor cells are more sensitive to Hsp90 inhibition and that Hsp90 from tumor cells is more sensitive to small molecule inhibitors (eg 17AAG). The mechanism of this differential sensitivity of normal versus tumor Hsp90 is not known (although mutation has been ruled out). One possible mechanism may be differences in post-translational modification of tumor Hsp90.
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ID gène
- 3320
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NCBI Accession
- NP_001017963
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UniProt
- P07900
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Pathways
- M Phase, Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
Antigène
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