LRP5 anticorps (C-Term)
Aperçu rapide pour LRP5 anticorps (C-Term) (ABIN390099)
Antigène
Voir toutes LRP5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1538-1567, C-Term
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Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Immunogène
- This LRP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1538-1567 amino acids from the C-terminal region of human LRP5.
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Isotype
- Ig Fraction
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anti-Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) (AA 1000-1250) antibody
LRP5 Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) (Internal Region) antibodyVerified LRP5 Reactivité: Humain WB, IHC, ELISA Hôte: Chèvre Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) antibodyLRP5 Reactivité: Humain ELISA, FACS Hôte: Souris Monoclonal 2B11 unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) (AA 451-550) antibodyLRP5 Reactivité: Humain, Souris, Rat ELISA, IF (p), IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) (AA 769-1016) antibodyLRP5 Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) (AA 41-130) antibodyLRP5 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 1E9 unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) antibodyLRP5 Reactivité: Humain WB, FACS, EIA Hôte: Souris Monoclonal 2B11 unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) (AA 1538-1567) antibodyLRP5 Reactivité: Humain, Souris WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) (AA 102-336) antibodyLRP5 Reactivité: Rat WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) (AA 41-130) antibodyLRP5 Reactivité: Humain WB, ELISA Hôte: Souris Polyclonal unconjugated
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Indications d'application
- WB: 1:1000. IHC-P: 1:50~100
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Date de péremption
- 6 months
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- LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))
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Autre désignation
- LRP5
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Sujet
- Low density lipoprotein (LDL) receptor-related protein (LRP), a member of the LDL receptor family, binds multiple classes of ligands and has been implicated in a broad range of normal and disease processes involving lipid metabolism, protease clearance, and cell migration. Structurally, members of the LDLR family share homology within their extracellular domains, which are highlighted by the presence of clusters of ligand-binding repeats. LRP is a large endocytic receptor that participates in several biological pathways and plays prominent roles in lipoprotein metabolism and in the catabolism of proteinases involved in coagulation and fibrinolysis. LRP also mediates the cellular entry of certain viruses and toxins and facilitates the activation of various lysosomal enzymes. All LRPs are expressed in the central nervous system and, for most receptors, animal models have shown that they are indispensable for successful neurodevelopment. The mechanisms by which they regulate the formation of the nervous system are varied and include the transduction of extracellular signals and the modulation of intracellular signal propagation, as well as cargo transport, the function most commonly attributed to this gene family.
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Poids moléculaire
- 179145
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ID gène
- 4041
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NCBI Accession
- NP_002326
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UniProt
- O75197
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Pathways
- Signalisation WNT, Stem Cell Maintenance, Positive Regulation of fat Cell Differentiation
Antigène
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