NTSR2 anticorps
Aperçu rapide pour NTSR2 anticorps (ABIN317761)
Antigène
Voir toutes NTSR2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- NTR2 antibody detects endogenous levels of NTR2 protein.(region surrounding Asp184)
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Purification
- Affinity chromatography
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anti-Neurotensin Receptor 2 (NTSR2) (AA 377-392), (Intracellular) antibody
NTSR2 Reactivité: Rat WB, IHC, IF, IC Hôte: Lapin Polyclonal unconjugated
anti-Neurotensin Receptor 2 (NTSR2) (AA 359-410) antibodyNTSR2 Reactivité: Humain WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Neurotensin Receptor 2 (NTSR2) (Internal Region) antibodyNTSR2 Reactivité: Humain, Souris, Rat WB, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Neurotensin Receptor 2 (NTSR2) (C-Term) antibodyNTSR2 Reactivité: Humain IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Neurotensin Receptor 2 (NTSR2) (Extracellular Domain) antibodyNTSR2 Reactivité: Humain, Singe IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Neurotensin Receptor 2 (NTSR2) (AA 151-200) antibodyNTSR2 Reactivité: Humain, Souris, Rat WB, ELISA, IF Hôte: Lapin Polyclonal unconjugated
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Indications d'application
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ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1,0 mg/mL
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Buffer
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- NTSR2 (Neurotensin Receptor 2 (NTSR2))
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Autre désignation
- Neurotensin Receptor Type 2
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Sujet
- Neurotensin (NT) initiates an intracellular response by interacting with the G protein-coupled receptors NTR1 (NTS1 receptor, high affinity NTR) and NTR2 (NTS2 receptor, levocabastine-sensitive neurotensin receptor), and the type I receptor NTR3 (NTS3 receptor, sortilin-1, Gp95). NT has a wide distribution in regions of the brain and in peripheral tissues where NT receptors can contribute to hypotension, hyperglycemia, hypothermia, antinociception and regulation of intestinal motility and secretion. HL-60 cells express NTR1, which can couple to Gq, Gi/o or Gs. Alternative splicing of rat NTR2 can generate a 5-transmembrane domain variant isoform that is coexpressed with the full length NTR2 throughout the brain and spinal cord. NTR3 activation in the murine microglial cell line N11 induces MIP-2, MCP-1, IL-1β and TNFα in an ERK1/2 and Akt kinase-dependent manner.Synonyms: Levocabastine-sensitive neurotensin receptor, NT-R-2, NTR2, NTSR2
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Poids moléculaire
- approx. 45 kDa
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ID gène
- 23620
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NCBI Accession
- NP_036476
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UniProt
- O95665
Antigène
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