Cet anticorps anti-PDE8A Polyclonal Lapin (ABIN302523) détecte spécifiquement PDE8A dans IHC (p).
L’anticorps est réactif avec des échantillons de Humain.
Immunohistochemistry on paraffin sections (10 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
1.0 mg/mL
Buffer
PBS containing 0.09 % sodium azide as preservative
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.
Antigène
PDE8A
(phosphodiesterase 8A (PDE8A))
Autre désignation
PDE8A
Sujet
Phosphodiesterase 8A, a high affinity, cAMP-specific phosphodiesterase, has been implicated in penile erectile dysfunction. PDE8A activity is inhibited by dipyridamole, but not by rolipram, zaprinast, or IBMX. At least five splice variants and four protein isoforms have been reported.Synonyms: 5'-cyclic phosphodiesterase 8A, FLJ16150, High affinity cAMP-specific and IBMX-insensitive 3', HsT19550, Phosphodiesterase 8A, cAMP-specific cyclic nucleotide phosphodiesterase 8A