ROBO1 anticorps (AA 1625-1650)
(1 reference)
Aperçu rapide pour ROBO1 anticorps (AA 1625-1650) (ABIN129621)
Antigène
Voir toutes ROBO1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1625-1650
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N° du produit (Fournisseur)
- 600-401-692
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Fournisseur
- Rockland
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Fonction
- ROBO-1 Antibody
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Réactivité croisée (Details)
- This affinity purified antibody is directed against human ROBO-1 protein.
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Attributs du produit
- Synonyms: rabbit anti-ROBO1 antibody, ROBO 1, ROBO-1, hROBO-1, Roundabout homolog 1, Deleted in U twenty twenty, DUTT1, DUTT-1
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Purification
- The product was affinity purified from monospecific antiserum by immunoaffinity purification.
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Stérilité
- Sterile filtered
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Immunogène
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Immunogen: This affinity-purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an C-Terminal region near amino acids 1625-1650 of Human ROBO-1.
Immunogen Type: Conjugated Peptide
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Isotype
- IgG
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anti-Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1) (Internal Region) antibody
Verified ROBO1 Reactivité: Humain ELISA, IHC, IF Hôte: Chèvre Polyclonal unconjugated
anti-Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1) (AA 1452-1651) antibodyROBO1 Reactivité: Humain WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1) (AA 491-506), (Extracellular) antibodyROBO1 Reactivité: Humain WB, IHC, IF, FACS, LCI Hôte: Lapin Polyclonal unconjugated
anti-Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1) (Internal Region) antibodyVerified ROBO1 Reactivité: Souris WB, ELISA, IHC Hôte: Chèvre Polyclonal unconjugated
anti-Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1) (AA 491-589) antibodyROBO1 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 1F8 unconjugated
anti-Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1) (AA 29-143) antibodyROBO1 Reactivité: Humain WB, ELISA, IF Hôte: Lapin Polyclonal unconjugated
anti-Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1) (AA 1097-1130) antibodyROBO1 Reactivité: Humain WB Hôte: Lapin Polyclonal RB54414 unconjugated
anti-Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1) (AA 491-589) antibodyROBO1 Reactivité: Humain WB, ELISA Hôte: Souris Polyclonal unconjugated
anti-Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1) (Internal Region) antibodyROBO1 Reactivité: Humain, Souris, Rat WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1) (AA 491-506), (Extracellular) antibody (FITC)ROBO1 Reactivité: Humain FACS, LCI Hôte: Lapin Polyclonal FITC
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Indications d'application
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Immunohistochemistry Dilution: 2 μg/mL to 10 μg/mL
Application Note: This affinity purified antibody has been tested for use in ELISA, western blot, and immunohistochemistry. It may be suitable for immunofluorescence and IP. Specific conditions for reactivity should be optimized by the end user. Expect a band at ~181 kDa in size corresponding to ROBO-1 by western blotting in the appropriate cell lysate or extract.
Western Blot Dilution: 1:500 - 1:3,000
Immunoprecipitation Dilution: User Optimized
ELISA Dilution: 1:30,000 - 1:60,000
IF Microscopy Dilution: User Optimized
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.0 mg/mL
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Buffer
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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Date de péremption
- 12 months
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: "[Auditory neuropathy in children(analysis of 14 cases)]." dans: Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology, Vol. 19, Issue 1, pp. 19-21, (2006) (PubMed).
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- ROBO1 (Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1))
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Autre désignation
- ROBO1
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Sujet
- Background: ROBO-1 (also called Roundabout homolog 1 precursor and Deleted in U twenty twenty (DUTT)) functions as a receptor for SLIT1 and SLIT2. The SLIT proteins are thought to act as a molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex. ROBO-1 may also be required for lung development. ROBO-1 is a type I membrane protein. ROBO-1 is a widely expressed protein with the exception of the kidney. Defects in ROBO1 may be a cause of breast and lung cancer. ROBO-1 maps within a region of overlapping homozygous deletions characterized in both small cell lung cancer cell lines (SCLC) and in a breast cancer cell line. Multiple splice variants have been identified for this protein.
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ID gène
- 6091
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UniProt
- Q2M1J3
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Pathways
- Positive Regulation of Endopeptidase Activity
Antigène
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