SLC16A3 anticorps
Aperçu rapide pour SLC16A3 anticorps (ABIN317918)
Antigène
Voir toutes SLC16A3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Specificité
- This antibody detects endogenous levels of MCT4 protein.(region surrounding Phe265)
-
Purification
- Affinity Chromatography using epitope-specific immunogen.
-
-
anti-Solute Carrier Family 16 (Monocarboxylic Acid Transporters), Member 3 (SLC16A3) (AA 433-462), (C-Term) antibody
SLC16A3 Reactivité: Humain, Souris, Rat WB, IHC (p) Hôte: Lapin Polyclonal RB31368 unconjugated
anti-Solute Carrier Family 16 (Monocarboxylic Acid Transporters), Member 3 (SLC16A3) (AA 401-465) antibodySLC16A3 Reactivité: Humain, Souris, Rat WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Solute Carrier Family 16 (Monocarboxylic Acid Transporters), Member 3 (SLC16A3) (AA 371-465) antibodySLC16A3 Reactivité: Humain WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-Solute Carrier Family 16 (Monocarboxylic Acid Transporters), Member 3 (SLC16A3) (Internal Region) antibodySLC16A3 Reactivité: Humain, Souris, Rat WB, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Solute Carrier Family 16 (Monocarboxylic Acid Transporters), Member 3 (SLC16A3) (AA 406-465) antibodySLC16A3 Reactivité: Humain WB, ELISA, IF Hôte: Lapin Polyclonal unconjugated
anti-Solute Carrier Family 16 (Monocarboxylic Acid Transporters), Member 3 (SLC16A3) (AA 40-89) antibodySLC16A3 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Poisson zèbre (Danio rerio) WB Hôte: Lapin Polyclonal unconjugated
anti-Solute Carrier Family 16 (Monocarboxylic Acid Transporters), Member 3 (SLC16A3) (N-Term) antibodySLC16A3 Reactivité: Humain, Souris WB Hôte: Lapin Polyclonal unconjugated
anti-Solute Carrier Family 16 (Monocarboxylic Acid Transporters), Member 3 (SLC16A3) (AA 400-450) antibodySLC16A3 Reactivité: Humain WB, IP Hôte: Lapin Polyclonal unconjugated
anti-Solute Carrier Family 16 (Monocarboxylic Acid Transporters), Member 3 (SLC16A3) (AA 447-459), (Intracellular) antibodySLC16A3 Reactivité: Rat WB Hôte: Lapin Polyclonal unconjugated
-
-
Indications d'application
-
ELISA: 1/40000-1/60000. Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
-
-
-
Concentration
- 1.0 mg/mL
-
Buffer
- Phosphate buffered saline (PBS), pH ~7.2 with 0.05 % Sodium Azide as preservative
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freezing and thawing.
-
Stock
- 4 °C/-20 °C
-
Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- SLC16A3 (Solute Carrier Family 16 (Monocarboxylic Acid Transporters), Member 3 (SLC16A3))
-
Autre désignation
- SLC16A3
-
Sujet
- Monocarboxylates, such as lactate and pyruvate, play an integral role in cellular metabolism. Lactic acid is produced in large quantities as a result of glycolysis, which provides the majority of ATP to cells under normal physiological conditions. However, accumulation of lactic acid leads to a decrease in intracellular pH and cessation of glycolysis. In order for glycolysis to continue at a high rate, lactic acid must be transported out of the cell. This transport process is carried out by a family of monocarboxylate transporters (MCTs),which function as proton symports and are stereoselective for L-lactate.The MCT family consists of at least eight members, MCT1-8, which contain between 10-12 transmembrane-helical (TM) domains, with the amino and carboxy termini located in the cytoplasm. MCT1 is widely expressed and is the major form of MCTs in tumor cells and erythrocytes. MCT2 is highly expressed in liver and testis, while MCT3 and MCT4 are predominantly expressed in skeletal muscle.Synonyms: MCT 3, MCT 4, MCT3, MCT4, Monocarboxylate transporter 3, Monocarboxylate transporter 4, Solute carrier family 16 member 3
-
Poids moléculaire
- approx. 49 kDa
-
ID gène
- 9123
-
NCBI Accession
- NP_001035887
-
UniProt
- O15427
-
Pathways
- L'effet Warburg
Antigène
-
