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SPTLC1 anticorps (C-Term)

Cité dans 2 publications. Cet anticorps anti-SPTLC1 Polyclonal Lapin (Clone RB4727) (ABIN389109) détecte spécifiquement SPTLC1 dans WB. L’anticorps est réactif avec des échantillons de Humain.
N° du produit ABIN389109
467,50 €
Plus frais de livraison 40,00 € et TVA
Destination: France
Envoi sous 14 à 17 jours ouvrables

Aperçu rapide pour SPTLC1 anticorps (C-Term) (ABIN389109)

Antigène

Voir toutes SPTLC1 Anticorps
SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))

Reactivité

  • 61
  • 22
  • 9
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Humain

Hôte

  • 62
  • 1
Lapin

Clonalité

  • 62
  • 1
Polyclonal

Conjugué

  • 26
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp SPTLC1 est non-conjugé

Application

  • 50
  • 21
  • 13
  • 13
  • 11
  • 7
  • 5
  • 4
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB)

Clone

RB4727
  • Épitope

    • 15
    • 7
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 405-437, C-Term

    Purification

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    Immunogène

    This SPTLC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 405-437 amino acids from the C-terminal region of human SPTLC1.

    Isotype

    Ig Fraction
  • Indications d'application

    WB: 1:1000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Date de péremption

    6 months
  • Wei, Yerokun, Leipelt, Haynes, Radhakrishna, Momin, Kelly, Park, Wang, Carton, Uhlinger, Merrill: "Serine palmitoyltransferase subunit 1 is present in the endoplasmic reticulum, nucleus and focal adhesions, and functions in cell morphology." dans: Biochimica et biophysica acta, Vol. 1791, Issue 8, pp. 746-56, (2009) (PubMed).

    Medler, Petrusca, Lee, Hubbard, Berdyshev, Skirball, Kamocki, Schuchman, Tuder, Petrache: "Apoptotic sphingolipid signaling by ceramides in lung endothelial cells." dans: American journal of respiratory cell and molecular biology, Vol. 38, Issue 6, pp. 639-46, (2008) (PubMed).

  • Antigène

    SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))

    Autre désignation

    SPTLC1

    Sujet

    Serine palmitoyltransferase (SPT) is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine.

    Poids moléculaire

    52744

    ID gène

    10558

    NCBI Accession

    NP_001268232, NP_006406, NP_847894

    UniProt

    O15269
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