SPTLC1 anticorps (C-Term)

N° du produit ABIN3044549

Détail du produit anti-SPTLC1 anticorps

Antigène: SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))

Épitope: AA 444-473, C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPTLC1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Serine palmitoyltransferase 1(SPTLC1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Séquence: IRVVVTVEQT EEELERAAST IKEVAQAVLL

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Serine palmitoyltransferase 1(SPTLC1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: serine palmitoyltransferase, long chain base subunit 1
Protein Name: Serine palmitoyltransferase 1

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human SPTLC1 (444-473aa IRVVVTVEQTEEELERAASTIKEVAQAVLL), different from the related mouse sequence by three amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur SPTLC1

Antigène: SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))

Autre désignation: SPTLC1 (SPTLC1 Produits)

Synonymes: anticorps ATSPT1, anticorps SERINE PALMITOYLTRANSFERASE 1, anticorps serine palmitoyltransferase 1, anticorps Afu6g00300, anticorps HSAN1, anticorps HSN1, anticorps LBC1, anticorps LCB1, anticorps SPT1, anticorps SPTI, anticorps wu:fc75h04, anticorps wu:fp41c08, anticorps zgc:112247, anticorps AW552086, anticorps C77762, anticorps E030036H05, anticorps Lcb1, anticorps RGD1306617, anticorps Spt1, anticorps serine palmitoyltransferase 1, anticorps Serine palmitoyltransferase 1, anticorps serine palmitoyltransferase long chain base subunit 1, anticorps serine palmitoyltransferase, long chain base subunit 1, anticorps serine palmitoyltransferase, long chain base subunit 1 L homeolog, anticorps SPT1, anticorps AFUA_6G00300, anticorps PAS_FragB_0040, anticorps SPTLC1, anticorps sptlc1, anticorps sptlc1.L, anticorps Sptlc1

Sujet: SPTLC1(Serine palmitoyltransferase, long chain base subunit 1), also known as SPT1, LCB1, is a protein which in humans is encoded by the SPTLC1 gene. Dawkins et al. (2001) noted that the SPTLC1 gene maps to chromosome 9q22.1-q22.3. Serine palmitoyltransferase, which consists of two different subunits, is the initial enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. The product of this gene is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified.

Synonyms: HSAN antibody|HSAN1 antibody|HSN1 antibody|LBC1 antibody|LCB 1 antibody|LCB1 antibody|Long chain base biosynthesis protein 1 antibody| MGC14645 antibody|Serine C palmitoyltransferase antibody|Serine palmitoyl CoA transferase 1 antibody|Serine palmitoyltransferase 1 antibody|Serine palmitoyltransferase long chain base subunit 1 antibody|Serine palmitoyl transferase subunit 1 antibody|Serine-palmitoyl-CoA transferase 1 antibody|SPT 1 antibody| SPT1 antibody|SPTC1_HUMAN antibody|SPTI antibody|SPTLC 1 antibody|SPTLC1 antibody

ID gène: 10558

UniProt: O15269