SUMO2/3 anticorps (C-Term)
(8 références)Aperçu rapide pour SUMO2/3 anticorps (C-Term) (ABIN388034)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 49-81, C-Term
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Homologie
- X, Zf, B, C, Ha, Pr, Pig
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This SUMO2/3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-81 amino acids from the C-terminal region of human SUMO2/3.
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Isotype
- IgG
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anti-Small Ubiquitin Related Modifier 2/3 (SUMO2/3) (full length) antibody
SUMO2/3 Reactivité: Humain, Souris, Rat WB, IF, ELISA, IHC (fro) Hôte: Rat Monoclonal 3H12 unconjugated
anti-Small Ubiquitin Related Modifier 2/3 (SUMO2/3) (AA 49-81) antibodySUMO2/3 Reactivité: Humain, Souris, Rat WB, IF, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier 2/3 (SUMO2/3) (AA 53-84), (C-Term) antibodySUMO2/3 Reactivité: Humain WB, IF, IHC (p) Hôte: Lapin Polyclonal RB15398 unconjugated
anti-Small Ubiquitin Related Modifier 2/3 (SUMO2/3) (AA 53-84) antibodySUMO2/3 Reactivité: Humain WB, IF, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier 2/3 (SUMO2/3) (AA 38-64) antibodySUMO2/3 Reactivité: Humain WB Hôte: Lapin Polyclonal RB3377 unconjugated
anti-Small Ubiquitin Related Modifier 2/3 (SUMO2/3) (cleaved), (Gly93) antibodySUMO2/3 Reactivité: Humain, Souris, Rat WB, ELISA Hôte: Lapin Polyclonal unconjugated
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Indications d'application
- IF: 1:100. IF: 1:100. WB: 1:2000. IHC-P: 1:50~100
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Date de péremption
- 6 months
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: "Adenovirus E4-ORF3 Targets PIAS3 and Together with E1B-55K Remodels SUMO Interactions in the Nucleus and at Virus Genome Replication Domains." dans: Journal of virology, Vol. 89, Issue 20, pp. 10260-72, (2015) (PubMed).
: "Signaling via the IL-20 receptor inhibits cutaneous production of IL-1β and IL-17A to promote infection with methicillin-resistant Staphylococcus aureus." dans: Nature immunology, Vol. 14, Issue 8, pp. 804-11, (2013) (PubMed).
: "PKC? mediates disturbed flow-induced endothelial apoptosis via p53 SUMOylation." dans: The Journal of cell biology, Vol. 193, Issue 5, pp. 867-84, (2011) (PubMed).
: "Lysine deacetylation in ischaemic preconditioning: the role of SIRT1." dans: Cardiovascular research, Vol. 89, Issue 3, pp. 643-9, (2011) (PubMed).
: "Keratin hypersumoylation alters filament dynamics and is a marker for human liver disease and keratin mutation." dans: The Journal of biological chemistry, Vol. 286, Issue 3, pp. 2273-84, (2011) (PubMed).
: "Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress." dans: Disease models & mechanisms, Vol. 3, Issue 9-10, pp. 595-604, (2010) (PubMed).
: "Spatial interplay between PIASy and FIP200 in the regulation of signal transduction and transcriptional activity." dans: Molecular and cellular biology, Vol. 28, Issue 8, pp. 2771-81, (2008) (PubMed).
: "SUMO modification of the Ets-related transcription factor ERM inhibits its transcriptional activity." dans: The Journal of biological chemistry, Vol. 280, Issue 26, pp. 24330-8, (2005) (PubMed).
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- SUMO2/3 (Small Ubiquitin Related Modifier 2/3 (SUMO2/3))
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Autre désignation
- SUMO2/3
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Sujet
- SUMO2 and SUMO3 are members of the SUMO (small ubiquitin-like modifier) protein family. This protein family functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. In vertebrates, three members of the SUMO family have been described, SUMO 1 and the functionally distinct homologues SUMO 2 and SUMO 3. SUMO modification sites present in the N terminal regions of SUMO 2 and SUMO 3 are utilized by SAE1/SAE2 (SUMO E1) and Ubc9 (SUMO E2) to form polymeric chains of SUMO 2 and SUMO 3 on protein substrates, a property not shared by SUMO 1.
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Poids moléculaire
- 11637
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ID gène
- 6612
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NCBI Accession
- NP_008867
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UniProt
- P55854
Antigène
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