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TGFBR1 anticorps (AA 134-163)

Il existe 4+ publications pour ce produit. L’anticorps anti-TGFBR1 Polyclonal Lapin est utilisé pour la détection de TGFBR1 dans des échantillons de Humain. Il a été validé pour WB et IHC.

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. (TGFBR1 anticorps (AA 134-163))

IHC (p)

2 images

(4 références)

N° du produit ABIN392279

434,77 €

Plus frais de livraison 40,00 € et TVA

Destination: France

Envoi sous 14 à 17 jours ouvrables

Aperçu rapide pour TGFBR1 anticorps (AA 134-163) (ABIN392279)

Antigène

Voir toutes TGFBR1 Anticorps

TGFBR1 (Transforming Growth Factor, beta Receptor 1 (TGFBR1))

Reactivité

Humain

Hôte

Lapin

Clonalité

Polyclonal

Conjugué

Cet anticorp TGFBR1 est non-conjugé

Application

Western Blotting (WB), Immunohistochemistry (IHC)

Clone

RB03530

Discover our top product TGFBR1 Anticorps primaire

Épitope
9

8

5

5

4

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 134-163

Homologie

B, M, Pig, Rat

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène

This TGF Beta Receptor I antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-163 amino acids from the Central region of human TGF Beta Receptor I.

Isotype

Ig Fraction
anti-Transforming Growth Factor, beta Receptor 1 (TGFBR1) (AA 30-125) antibody
TGFBR1 Reactivité: Humain WB, ELISA Hôte: Souris Polyclonal unconjugated

anti-Transforming Growth Factor, beta Receptor 1 (TGFBR1) (AA 50-63) antibody
Verified TGFBR1 Reactivité: Humain, Rat WB, ELISA, IHC, FACS Hôte: Chèvre Polyclonal unconjugated

anti-Transforming Growth Factor, beta Receptor 1 (TGFBR1) (pSer165) antibody
TGFBR1 Reactivité: Humain WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated

anti-Transforming Growth Factor, beta Receptor 1 (TGFBR1) (AA 157-244) antibody
TGFBR1 Reactivité: Humain WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated

anti-Transforming Growth Factor, beta Receptor 1 (TGFBR1) (AA 34-124) antibody
TGFBR1 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated

anti-Transforming Growth Factor, beta Receptor 1 (TGFBR1) (AA 162-403) antibody
TGFBR1 Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated

anti-Transforming Growth Factor, beta Receptor 1 (TGFBR1) (Tyr159) antibody
TGFBR1 Reactivité: Humain, Souris, Rat WB, ELISA, IF Hôte: Lapin Polyclonal unconjugated

anti-Transforming Growth Factor, beta Receptor 1 (TGFBR1) antibody
TGFBR1 Reactivité: Humain, Souris, Rat ELISA, IHC Hôte: Lapin Polyclonal unconjugated

anti-Transforming Growth Factor, beta Receptor 1 (TGFBR1) antibody
TGFBR1 Reactivité: Humain, Souris, Rat WB, ELISA, IF Hôte: Lapin Polyclonal unconjugated

anti-Transforming Growth Factor, beta Receptor 1 (TGFBR1) (AA 145-172) antibody
TGFBR1 Reactivité: Humain, Souris WB Hôte: Lapin Polyclonal RB43638 unconjugated

Indications d'application

WB: 1:1000. IHC-P: 1:50~100

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation

Avoid freeze-thaw cycles.

Stock

4 °C,-20 °C

Stockage commentaire

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

Date de péremption

6 months
Yi, Li, Nie, Jia, Zhang, Wang, Wang: "Effect of astragalus injection on renal tubular epithelial transdifferentiation in type 2 diabetic mice." dans: BMC complementary and alternative medicine, Vol. 16, pp. 222, (2017) (PubMed).

Zhang, Chang, Li, Gao, Wang, Ma, Li, Wang: "miR-140-5p regulates adipocyte differentiation by targeting transforming growth factor-β signaling." dans: Scientific reports, Vol. 5, pp. 18118, (2016) (PubMed).

Hou, Wu, Wei, Ren, Du, Wu, Li, Shi: "CD36 is involved in high glucose-induced epithelial to mesenchymal transition in renal tubular epithelial cells." dans: Biochemical and biophysical research communications, Vol. 468, Issue 1-2, pp. 281-6, (2015) (PubMed).

Miles, Tung, Aguiar, Kurtoglu, Sikes: "Increased TGF-?1-mediated suppression of growth and motility in castrate-resistant prostate cancer cells is consistent with Smad2/3 signaling." dans: The Prostate, Vol. 72, Issue 12, pp. 1339-50, (2012) (PubMed).
Antigène

TGFBR1 (Transforming Growth Factor, beta Receptor 1 (TGFBR1))

Autre désignation

TGF beta Receptor I (TGFBR1)

Sujet

The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS).

Poids moléculaire

55960

ID gène

7046

NCBI Accession

NP_001124388, NP_004603

UniProt

P36897

Pathways

Growth Factor Binding