TNFRSF18 anticorps (C-Term)
Aperçu rapide pour TNFRSF18 anticorps (C-Term) (ABIN184156)
Antigène
Voir toutes TNFRSF18 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- LRSQCMWPRE TQLLLEVPPS TEDARSCQFP EEERGERSAE EKGRLGDLWV
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Homologie
- Human: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against TNFRSF18. It was validated on Western Blot and immunohistochemistry.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human TNFRSF18
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 241 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))
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Autre désignation
- TNFRSF18
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Sujet
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The protein encoded by TNFRSF18 is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death.
Alias Symbols: AITR, GITR, CD357, GITR-D
Protein Interaction Partner: LNX1, TRAF3, TRAF2, TRAF1, TNFSF18, TNFRSF18,
Protein Size: 241 -
Poids moléculaire
- 26 kDa
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ID gène
- 8784
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NCBI Accession
- NM_004195, NP_004186
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UniProt
- Q9Y5U5
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Pathways
- Cancer Immune Checkpoints
Antigène
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