TNFRSF18 anticorps (AA 266-162)

N° du produit ABIN7092879

Détail du produit anti-TNFRSF18 anticorps

Antigène: TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))

Épitope: AA 266-162

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp TNFRSF18 est non-conjugé

Application: Flow Cytometry (FACS), ELISA

Purification: Purified from cell culture supernatant by affinity chromatography

Immunogène: Recombinant human GITR (Gln266-Pro162) (ABIN6961091) produced by using human HEK293 cells

Clone: DM78

Isotype: IgG

Information d'application

Indications d'application: ELISA 1/5000-10000,Flow Cyt  1/100

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.,0.1 % Procline 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détails sur TNFRSF18

Antigène: TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))

Autre désignation: GITR (TNFRSF18 Produits)

Synonymes: anticorps GITR, anticorps TNFRSF18, anticorps AITR, anticorps Gitr, anticorps CD357, anticorps GITR-D, anticorps TNF receptor superfamily member 18, anticorps tumor necrosis factor receptor superfamily, member 18, anticorps TNFRSF18, anticorps Tnfrsf18

Sujet: Synonyms:AITR, GITR, TNFRSF18, CD357
Description:This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Poids moléculaire: 26.0kDa

ID gène: 8784

UniProt: Q9Y5U5

Pathways: Cancer Immune Checkpoints