LTBR anticorps (Extracellular Domain) (PE)
Aperçu rapide pour LTBR anticorps (Extracellular Domain) (PE) (ABIN317402)
Antigène
Voir toutes LTBR AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- Extracellular Domain
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Specificité
- This antibody recognises lymphotoxin-beta receptor (LT beta R), a member of the tumour necrosis factor family. LT beta R is primarily expressed on stromal cells and fibroblasts and at lower levels on myeloid cell lines. Clone 5G11b specifically recognises surface expressed LT beta R. The clone is reported to be agonistic with respect to NF Kappa B activation, MIP-2 induction and IL-6 release (2). This product is routinely tested on mouse WEHI cells.
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Attributs du produit
- Synonyms: Tumor necrosis factor receptor 3, TNF-R3, Tumor necrosis factor C receptor, TNFCR,TNFRSF3, D12S370, Lymphotoxin-beta receptor, Tumor necrosis factor receptor superfamilymember 3, Tumor necrosis factor receptor type III, Tumor necrosis factor receptor 2-relatedprotein
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Purification
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
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Immunogène
- Recombinant extracellular domain of LT beta R
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Isotype
- IgG2a
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anti-Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) (AA 66-215) antibody
LTBR Reactivité: Humain WB, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) (AA 31-227) antibodyLTBR Reactivité: Humain, Souris WB, ELISA, FACS Hôte: Souris Monoclonal 1D1C5C8 unconjugated
anti-Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) (N-Term) antibodyLTBR Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) (AA 128-395) antibodyLTBR Reactivité: Souris WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) (AA 31-224) antibodyLTBR Reactivité: Humain ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) (AA 31-227) antibodyLTBR Reactivité: Humain WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) (AA 66-215) antibodyLTBR Reactivité: Humain WB Hôte: Souris Monoclonal C1 unconjugated
anti-Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) antibodyKD Validated LTBR Reactivité: Humain WB Hôte: Souris Monoclonal 24GB6730 unconjugated
anti-Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) (AA 1-435) antibodyLTBR Reactivité: Humain WB Hôte: Souris Polyclonal unconjugated
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Indications d'application
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Flow Cytometry: use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Reconstitution
- Reconstitute with 1.0 mL distilled water
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Concentration
- 0.05 mg/mL
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Buffer
- Phosphate buffered saline pH 7.4, 0.09 % Sodium Azide, 1 % Bovine Serum Albumin
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
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Store the antibody prior and following reconstitution at 2-8 °C. DO NOT FREEZE. This product is photosensitive and should be protected from light.
Shelf life: One year from despatch. -
Date de péremption
- 12 months
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- LTBR (Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR))
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Autre désignation
- LTBR / TNFR3
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Sujet
- The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein specifically binds the lymphotoxin membrane form (a complex of lymphotoxin alpha and lymphtoxin beta). The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and tranformed cells. Activation of the encoded protein can trigger apoptosis.Synonyms: D12S370, Lymphotoxin-beta receptor, TNF-R3, TNFCR, TNFRSF3, Tumor necrosis factor C receptor, Tumor necrosis factor receptor 2-related protein, Tumor necrosis factor receptor 3, Tumor necrosis factor receptor superfamily member 3, Tumor necrosis factor receptor type III
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ID gène
- 4055
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UniProt
- P36941
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Pathways
- Signalisation NF-kappaB
Antigène
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