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VCAM1 anticorps

Il existe 2+ publications pour ce produit. L’anticorps anti-VCAM1 Monoclonal Rat est utilisé pour la détection de VCAM1 dans des échantillons de Souris. Il a été validé pour WB, FACS, IP, IHC (fro), BR et Adh Act.
N° du produit ABIN135074
438,91 €
Plus frais de livraison 40,00 € et TVA
500 μg
Destination: France
Envoi sous 7 à 10 jours ouvrables

Aperçu rapide pour VCAM1 anticorps (ABIN135074)

Antigène

Voir toutes VCAM1 Anticorps
VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

Reactivité

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Souris

Hôte

  • 105
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Rat

Clonalité

  • 185
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Monoclonal

Conjugué

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Cet anticorp VCAM1 est non-conjugé

Application

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Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Blocking Reagent (BR), Adhesion Activation (Adh Act)

Clone

M-K-2
  • Fonction

    Rat Anti-Mouse CD106-LE/AF

    Specificité

    Mouse CD106, Mr 100-110 kDa

    Attributs du produit

    Low Endotoxin/Azide Free Anti-Mouse CD106 antibody for use in flow cytometry, immunohistochemistry, western blotting, immunoprecipitation, blocking, and adhesion assays.

    niveau d'endotoxine

    Low Endotoxin

    Immunogène

    BALB/3T3 and +/+2.4 cells

    Isotype

    IgG1
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.5 mg/mL

    Buffer

    Phosphate buffered saline, pH 7.4

    Agent conservateur

    Azide free

    Conseil sur la manipulation

    Each reagent is stable for the period shown on the bottle label if stored as directed.

    Stock

    4 °C

    Stockage commentaire

    2-8°C
  • Gilchrist, Kinchesh, Zarghami, Khrapitchev, Sibson, Kersemans, Smart: "Improved detection of molecularly targeted iron oxide particles in mouse brain using B0 field stabilised high resolution MRI." dans: Magnetic resonance imaging, Vol. 67, pp. 101-108, (2020) (PubMed).

    Zarghami, Khrapitchev, Perez-Balderas, Soto, Larkin, Bau, Sibson: "Optimization of molecularly targeted MRI in the brain: empirical comparison of sequences and particles." dans: International journal of nanomedicine, Vol. 13, pp. 4345-4359, (2018) (PubMed).

  • Antigène

    VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

    Autre désignation

    CD106

    Sujet

    VCAM-1 is an adhesion molecule and a major mediator of the inflammatory response. It is expressed on activated microvascular endothelial cells in response to signals arising from immune responses in infection, graft rejection, tumor recognition and killing. The complementary binding ligand for VCAM-1 is VLA-4/CD49d. In addition to VCAM-1, VLA-4 also recognizes the extracellular matrix molecule fibronectin. This pairing of VCAM-1 and VLA-4 is able to provide a second signal (i.e., non-antigen specific) for T cell stimulation, such as that seen in transplantation. The monoclonal antibody MK-2 has been used in transplant studies to suppress cardiac rejection and induce long-term cardiac graft survival. In addition to inflammatory responses, VCAM-1 has a significant role in hemopoiesis through its ability to retain lymphocyte and myeloid precursors on stromal cells in the marrow and lymphoid organs. CD106/VCAM-1 exists as an integral membrane protein.

    ID gène

    22329

    UniProt

    P29533

    Pathways

    Carbohydrate Homeostasis
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