anti-ADAM Metallopeptidase Domain 22 (ADAM22) Anticorps

ADAM22 encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. De plus, nous expédions ADAM22 Kits (9) et ADAM22 Protéines (8) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
ADAM22 11496 Q9R1V6
ADAM22 57033  
ADAM22 53616 Q9P0K1
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Top anti-ADAM22 Anticorps sur anticorps-enligne.fr

Showing 10 out of 135 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Souris HRP ICC, IF, IP, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-ADAM22 (extracellular) Monoclonal Antibody, Clone S57-2 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-ADAM22 (extracellular) Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Membrane. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) ADAM22 (extracellular) Antibody (D) Composite. Western Blot analysis of Rat brain lysates showing detection of ADAM22 protein using Mouse Anti-ADAM22 Monoclonal Antibody, Clone S57-2 . Primary Antibody: Mouse Anti-ADAM22 Monoclonal Antibody  at 1:250, 1:500, and 1:1000. 100 μg Connectez-vous pour afficher 2 to 3 Days
$422.40
Détails
Humain Souris HRP ICC, IF, IHC, IP, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-ADAM22 (cytoplasmic) Monoclonal Antibody, Clone S46-30 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-ADAM22 (cytoplasmic) Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:200 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60 min at RT, 5 min at RT. Localization: Cell Membrane, Cytoplasm. Magnification: 60X. Western Blot analysis of Rat brain membrane lysate showing detection of ADAM22 protein using Mouse Anti-ADAM22 Monoclonal Antibody, Clone S46-30 . Primary Antibody: Mouse Anti-ADAM22 Monoclonal Antibody  at 1:100. 100 μg Connectez-vous pour afficher 2 to 3 Days
$422.40
Détails
Humain Souris FITC ICC, IF, IP, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-ADAM22 (extracellular) Monoclonal Antibody, Clone S57-2 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-ADAM22 (extracellular) Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Membrane. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) ADAM22 (extracellular) Antibody (D) Composite. Western Blot analysis of Rat brain lysates showing detection of ADAM22 protein using Mouse Anti-ADAM22 Monoclonal Antibody, Clone S57-2 . Primary Antibody: Mouse Anti-ADAM22 Monoclonal Antibody  at 1:250, 1:500, and 1:1000. 100 μg Connectez-vous pour afficher 2 to 3 Days
$426.80
Détails
Humain Souris FITC ICC, IF, IHC, IP, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-ADAM22 (cytoplasmic) Monoclonal Antibody, Clone S46-30 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-ADAM22 (cytoplasmic) Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:200 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60 min at RT, 5 min at RT. Localization: Cell Membrane, Cytoplasm. Magnification: 60X. Western Blot analysis of Rat brain membrane lysate showing detection of ADAM22 protein using Mouse Anti-ADAM22 Monoclonal Antibody, Clone S46-30 . Primary Antibody: Mouse Anti-ADAM22 Monoclonal Antibody  at 1:100. 100 μg Connectez-vous pour afficher 2 to 3 Days
$426.80
Détails
Humain Souris Alkaline Phosphatase (AP) ICC, IF, IP, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-ADAM22 (extracellular) Monoclonal Antibody, Clone S57-2 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-ADAM22 (extracellular) Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Membrane. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) ADAM22 (extracellular) Antibody (D) Composite. Western Blot analysis of Rat brain lysates showing detection of ADAM22 protein using Mouse Anti-ADAM22 Monoclonal Antibody, Clone S57-2 . Primary Antibody: Mouse Anti-ADAM22 Monoclonal Antibody  at 1:250, 1:500, and 1:1000. 100 μg Connectez-vous pour afficher 2 to 3 Days
$429.00
Détails
Humain Souris Alkaline Phosphatase (AP) ICC, IF, IHC, IP, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-ADAM22 (cytoplasmic) Monoclonal Antibody, Clone S46-30 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-ADAM22 (cytoplasmic) Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:200 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60 min at RT, 5 min at RT. Localization: Cell Membrane, Cytoplasm. Magnification: 60X. Western Blot analysis of Rat brain membrane lysate showing detection of ADAM22 protein using Mouse Anti-ADAM22 Monoclonal Antibody, Clone S46-30 . Primary Antibody: Mouse Anti-ADAM22 Monoclonal Antibody  at 1:100. 100 μg Connectez-vous pour afficher 2 to 3 Days
$429.00
Détails
Humain Souris Biotin ICC, IF, IP, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-ADAM22 (extracellular) Monoclonal Antibody, Clone S57-2 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-ADAM22 (extracellular) Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Membrane. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) ADAM22 (extracellular) Antibody (D) Composite. Western Blot analysis of Rat brain lysates showing detection of ADAM22 protein using Mouse Anti-ADAM22 Monoclonal Antibody, Clone S57-2 . Primary Antibody: Mouse Anti-ADAM22 Monoclonal Antibody  at 1:250, 1:500, and 1:1000. 100 μg Connectez-vous pour afficher 2 to 3 Days
$431.20
Détails
Humain Souris Biotin ICC, IF, IHC, IP, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-ADAM22 (cytoplasmic) Monoclonal Antibody, Clone S46-30 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-ADAM22 (cytoplasmic) Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:200 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60 min at RT, 5 min at RT. Localization: Cell Membrane, Cytoplasm. Magnification: 60X. Western Blot analysis of Rat brain membrane lysate showing detection of ADAM22 protein using Mouse Anti-ADAM22 Monoclonal Antibody, Clone S46-30 . Primary Antibody: Mouse Anti-ADAM22 Monoclonal Antibody  at 1:100. 100 μg Connectez-vous pour afficher 2 to 3 Days
$431.20
Détails
Humain Souris PE ICC, IF, IP, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-ADAM22 (extracellular) Monoclonal Antibody, Clone S57-2 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-ADAM22 (extracellular) Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Membrane. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) ADAM22 (extracellular) Antibody (D) Composite. Western Blot analysis of Rat brain lysates showing detection of ADAM22 protein using Mouse Anti-ADAM22 Monoclonal Antibody, Clone S57-2 . Primary Antibody: Mouse Anti-ADAM22 Monoclonal Antibody  at 1:250, 1:500, and 1:1000. 100 μg Connectez-vous pour afficher 2 to 3 Days
$432.30
Détails

ADAM22 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-ADAM22 Anticorps mieux référencés

  1. Mammalian Monoclonal ADAM22 Primary Antibody pour ISt, IHC - ABIN1304515 : Zhou, Lee, Jin, Wright, Smith, Anderson: Arrested maturation of excitatory synapses in autosomal dominant lateral temporal lobe epilepsy. dans Nature medicine 2009 (PubMed)
    Show all 6 Pubmed References

  2. Mammalian Monoclonal ADAM22 Primary Antibody pour ISt, IHC - ABIN1304516 : Ogawa, Oses-Prieto, Kim, Horresh, Peles, Burlingame, Trimmer, Meijer, Rasband: ADAM22, a Kv1 channel-interacting protein, recruits membrane-associated guanylate kinases to juxtaparanodes of myelinated axons. dans The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre ADAM22 partenaires d’interaction

Mouse (Murine) ADAM Metallopeptidase Domain 22 (ADAM22) interaction partners

  1. LGI1 (Montrer LGI1 Anticorps) and ADAM22 form an essential synaptic organizing complex that coordinates the maturation of excitatory synapses by regulating the functional incorporation of PSD-95 (Montrer DLG4 Anticorps)

  2. Interaction proteomics revealed the interactors of Caspr2 (Montrer CNTNAP2 Anticorps), including CNTN2 (Montrer CNTN2 Anticorps), KCNAs, members of the ADAM family (ADAM22, ADAM23 (Montrer Adam23 Anticorps) and ADAM11 (Montrer ADAM11 Anticorps)), members of LGI family and MAGUKs (DLGs and MPPs (Montrer MPHOSPH6 Anticorps)).

  3. ADAM22 is an axonal component of the Kv1 (Montrer KCNA5 Anticorps) K+ channel (Montrer KCNC4 Anticorps) complex that recruits membrane-associated guanylate kinase (Montrer GUK1 Anticorps) to juxtaparanodes

  4. ADAM22 is closely involved in the correct functioning of the nervous system.

  5. study identified LGI1 (Montrer LGI1 Anticorps) as a specific binding partner of ADAM22 protein from mouse brain, and demonstrated the specific interaction between LGI1 (Montrer LGI1 Anticorps) and ADAM22

Human ADAM Metallopeptidase Domain 22 (ADAM22) interaction partners

  1. these results support the existence of a second mechanism, alternative to inhibition of protein secretion, by which ADLTE (Montrer LGI1 Anticorps)-causing LGI1 (Montrer LGI1 Anticorps) mutations exert their loss-of-function effect extracellularly, and suggest that interactions of LGI1 (Montrer LGI1 Anticorps) with both ADAM22 and ADAM23 (Montrer Adam23 Anticorps) play an important role in the molecular mechanisms leading to utosomal dominant lateral temporal epilepsy

  2. Disruption of LGI1 (Montrer LGI1 Anticorps)-ADAM22 interaction reduces synaptic AMPA (Montrer GRIA3 Anticorps) receptors in hippocampal neurons.

  3. Data suggest that ADAM22 plays roles in cell differentiation, cell migration, and resistance to endocrine therapy in breast cancer; ADAM22 may serve as biomarker for poor disease-free survival in breast cancer patients. [REVIEW]

  4. findings suggest that SRC-1 (Montrer SRC Anticorps) switches steroid-responsive tumors to a steroid-resistant state in which the SRC-1 (Montrer SRC Anticorps) target gene ADAM22 has a critical role

  5. Mutations in disintegrin domain sequence in ADAM22 gene is associted with reduced LGI4 (Montrer LGI4 Anticorps)-binding abilities resulting in epilepsy.

  6. Transgenic leucine-rich glioma-inactivated 4 (Lgi4 (Montrer LGI4 Anticorps)) and transgenic Adam22 proteins are both expressed in Schwann cells as well as in sensory neurons; binding of Lgi4 (Montrer LGI4 Anticorps) to axonal Adam22 is required on axons to drive myelin formation.

  7. role for the 14-3-3zeta (Montrer YWHAZ Anticorps)/ADAM 22 association in the regulation of cell adhesion and related signaling events

  8. demonstrated a functional role for ADAM22/14-3-3 (Montrer YWHAQ Anticorps) in cell adhesion and spreading

  9. ADAM22, a brain-specific (Montrer CALY Anticorps) cell surface protein (Montrer CD28 Anticorps), mediates growth inhibition using an integrin dependent pathway. It is expressed in normal brain but not in high-grade gliomas.

  10. This study indicated ADAM22 gene is probably not a major gene for this epilepsy syndrome.

ADAM22 profil antigène

Profil protéine

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Unlike other members of the ADAM protein family, the protein encoded by this gene lacks metalloprotease activity since it has no zinc-binding motif. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. In mice, it has been shown to be essential for correct myelination in the peripheral nervous system. Alternative splicing results in several transcript variants.

Gene names and symbols associated with ADAM22

  • a disintegrin and metallopeptidase domain 22 (Adam22) anticorps
  • ADAM metallopeptidase domain 22 (Adam22) anticorps
  • ADAM metallopeptidase domain 22 (ADAM22) anticorps
  • ADAM metallopeptidase domain 22 L homeolog (adam22.L) anticorps
  • 2900022I03Rik anticorps
  • ADAM 22 anticorps
  • AI854032 anticorps
  • mdc2 anticorps
  • mdc11b anticorps

Protein level used designations for ADAM22

a disintegrin and metalloprotease domain (ADAM) 22 , disintegrin and metalloproteinase domain-containing protein 22 , a disintegrin and metalloprotease domain 22 , a disintegrin and metalloproteinase domain 22 , metalloproteinase-disintegrin ADAM22-3 , metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2 , ADAM 22 , MDC11.2 , metalloprotease-disintegrin MDC11b , metalloprotease/disintegrin xMDC11.2

GENE ID SPECIES
11496 Mus musculus
57033 Rattus norvegicus
53616 Homo sapiens
386621 Xenopus laevis
Fournisseurs de qualité sélectionnés pour anti-ADAM22 (ADAM22) Anticorps
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