anti-Baculoviral IAP Repeat-Containing 6 (BIRC6) Anticorps

BIRC6 encodes a protein with a BIR (baculoviral inhibition of apoptosis protein repeat) domain and a UBCc (ubiquitin-conjugating enzyme E2, catalytic) domain. De plus, nous expédions BIRC6 Kits (8) et et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
BIRC6 57448 Q9NR09
BIRC6 12211 O88738
BIRC6 313876  
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Top anti-BIRC6 Anticorps sur anticorps-enligne.fr

Showing 10 out of 66 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué ICC, IF, IHC (p), IP, IHC, PLA, WB Detection of Human BIRC6/Apollon by Western Blot and Immunoprecipitation using ABIN152603. Samples: A) Whole cell lysate (WCL) and S100 extract (S100) from HeLa cells. B) Whole cell lysate (10 mg) from HeLa cells. Chemiluminescence with an exposure time of 10 minutes. B) Immunoprecipitate was resolved by SDS-PAGE and stained with Coomassie Blue. The band that is BIRC6 was confirmed by mass spectrometry. Immunohistochemistry-Paraffin: BIRC6 Antibody [ABIN152603] - Human breast carcinoma. Antibody used at a dilution of 1:5,000 (0.2ug/ml). 100 μL Connectez-vous pour afficher 7 to 9 Days
$486.94
Détails
Humain Chèvre Inconjugué ELISA, WB   100 μg Connectez-vous pour afficher 6 to 7 Days
$221.76
Détails
Chien Souris Inconjugué IF, WB Western blot analysis of BRUCE on a SW-13 cell lysate (Human adrenal gland carcinoma, ATCC CCL-105). Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of the mouse anti-BRUCE antibody. Immunofluorescence staining of HeLa cells (Human cervical epitheloid carcinoma, ATCC CCL-2.2). 50 μg Connectez-vous pour afficher 6 to 8 Days
$154.07
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: BIRC6 Antibody [ABIN42847340] - Detection of Human BIRC6/Apollon byImmunohistochemistry. Sample: FFPE section of humanovarian tumor. Antibody: Affinity purified rabbit anti-BIRC6/Apollon used at a dilution of1:250. Detection: DAB staining. Detection of Human BIRC6/Apollon byImmunohistochemistry. Sample: FFPE section of humanmetastatic lymph node. Antibody: Affinity purified rabbit anti-BIRC6/Apollon used at a dilution of1:250. Detection: DAB staining. 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$538.13
Détails
Humain Chèvre Inconjugué ELISA, WB   100 μg Connectez-vous pour afficher 6 to 7 Days
$221.76
Détails
Humain Lapin Inconjugué EIA, IHC (p)   0.1 mg Connectez-vous pour afficher 12 to 15 Days
$375.38
Détails
Humain Chèvre Inconjugué IHC (p), ELISA 50 μg Connectez-vous pour afficher 7 to 9 Days
$451.00
Détails
Humain Lapin Inconjugué IF (p), IHC (p) Formalin-fixed and paraffin embedded human esophageal carcinoma labeled with Anti APOLLON/BIRC6 Polyclonal Antibody, Unconjugated (ABIN687292) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Connectez-vous pour afficher 3 to 7 Days
$295.90
Détails
Roussette (Chauve-souris) Chèvre Inconjugué ELISA   100 μg Connectez-vous pour afficher 7 to 9 Days
$507.83
Détails
Boeuf (Vache) Chèvre Inconjugué ELISA, ICC, IF   0.1 mg Connectez-vous pour afficher 7 to 9 Days
$317.63
Détails

BIRC6 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-BIRC6 Anticorps mieux référencés

  1. Human Polyclonal BIRC6 Primary Antibody pour ICC, IF - ABIN4284734 : Dong, Lin, Low, Vucic, English, Yee, Murray, Lam, Ling, Lam, Gout, Wang: Elevated expression of BIRC6 protein in non-small-cell lung cancers is associated with cancer recurrence and chemoresistance. dans Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2013 (PubMed)
    Show all 4 Pubmed References

  2. Cow (Bovine) Polyclonal BIRC6 Primary Antibody pour ELISA, ICC - ABIN4284735 : Lopergolo, Pennati, Gandellini, Orlotti, Poma, Daidone, Folini, Zaffaroni: Apollon gene silencing induces apoptosis in breast cancer cells through p53 stabilisation and caspase-3 activation. dans British journal of cancer 2009 (PubMed)

  3. Human Polyclonal BIRC6 Primary Antibody pour ICC, IF - ABIN152603 : Aharinejad, Andrukhova, Lucas, Zuckermann, Wieselthaler, Wolner, Grimm: Programmed cell death in idiopathic dilated cardiomyopathy is mediated by suppression of the apoptosis inhibitor Apollon. dans The Annals of thoracic surgery 2008 (PubMed)

  4. Dog (Canine) Monoclonal BIRC6 Primary Antibody pour IF, WB - ABIN968408 : Hauser, Bardroff, Pyrowolakis, Jentsch: A giant ubiquitin-conjugating enzyme related to IAP apoptosis inhibitors. dans The Journal of cell biology 1998 (PubMed)

Plus d’anticorps contre BIRC6 partenaires d’interaction

Human Baculoviral IAP Repeat-Containing 6 (BIRC6) interaction partners

  1. AVEN (Montrer AVEN Anticorps) and BIRC6 are inhibited by combination therapy of miR (Montrer MLXIP Anticorps)-30e and proanthocyanidin in glioblastoma stem cells

  2. Apollon expression is associated with the biological characteristics of esophageal squamous cell carcinoma (ESCC), and may be a valuable prognostic factor and a novel chemotherapeutic target for ESCC treatment.

  3. Apollon role in the multidrug resistance of human chronic myelogenous leukemia cells

  4. Apollon gene silencing can induce apoptosis and growth impairment in HeLa cells. In this regard, apollon can be considered a candidate therapeutic target in HeLa cells as a positive human papillomavirus cancer cell line.

  5. BRUCE protein was detected in 82% of tumors and tumor progression stage and invasion depth correlated significantly with BRUCE protein expression

  6. Results show that in addition to the scaffolding function in complex formation, BRUCE has an E3 ligase function to promote BRIT1 (Montrer MCPH1 Anticorps) deubiquitination by USP8 (Montrer USP8 Anticorps) leading to accumulation of BRIT1 (Montrer MCPH1 Anticorps) at DNA double-strand break.

  7. BIRC6 overexpression is a predictor of poor prognosis in colorectal cancer and could be a potential target for colorectal cancer therapy.

  8. The study demonstrates that the T allele of the rs2754511 in the BIRC6 gene plays a protective role in pseudoexfoliative glaucoma patients of the Pakistani population.

  9. Humanin signaling pathway via htHNR/JAKs/STAT3 (Montrer STAT3 Anticorps) increased the expression levels of mRNA and protein of Apollon/Bruce, an unusual member of the inhibitors of apoptosis proteins

  10. BRUCE acts as a scaffold, bridging the ubiquitin-specific peptidase 8 (USP8 (Montrer USP8 Anticorps)) and BRIT1 (Montrer MCPH1 Anticorps) in a complex to coordinate USP8 (Montrer USP8 Anticorps)-catalyzed deubiquitination of BRIT1 (Montrer MCPH1 Anticorps).

Cow (Bovine) Baculoviral IAP Repeat-Containing 6 (BIRC6) interaction partners

  1. The results of this study reveal the importance of BIRC6 expression for embryo survival during bovine preimplantation embryo development.

Mouse (Murine) Baculoviral IAP Repeat-Containing 6 (BIRC6) interaction partners

  1. Humanin signaling pathway via htHNR/JAKs/STAT3 (Montrer STAT3 Anticorps) increased the expression levels of mRNA and protein of Apollon/Bruce, an unusual member of the inhibitors of apoptosis proteins

  2. BRUCE acts as a scaffold, bridging the ubiquitin-specific peptidase 8 (USP8 (Montrer USP8 Anticorps)) and BRIT1 (Montrer MCPH1 Anticorps) in a complex to coordinate USP8 (Montrer USP8 Anticorps)-catalyzed deubiquitination of BRIT1 (Montrer MCPH1 Anticorps).

  3. BRUCE protects cells against apoptosis and functions as an inhibitor of apoptosis.

  4. BRUCE is broadly expressed in embryonic, extraembryonic, and adult mouse tissues, this bifunctional protein might play a unique role in normal trophoblast differentiation and embryonic survival

  5. p53 (Montrer TP53 Anticorps) is a downstream effector of Bruce, and, in response to loss of Bruce function, p53 (Montrer TP53 Anticorps) activates Pidd (Montrer PIDD Anticorps)/caspase-2 (Montrer CASP2 Anticorps) and Bax (Montrer BAX Anticorps)/Bak (Montrer BAK1 Anticorps), leading to mitochondrial apoptosis

  6. Birc6 plays a role in cell division

  7. These results establish a previously unrecognized link between NFAT (Montrer NFATC1 Anticorps) signaling and regulation of IAP (Montrer ALPI Anticorps) expression and are the first to identify a signaling pathway that increases BRUCE expression.

BIRC6 profil antigène

Profil protéine

This gene encodes a protein with a BIR (baculoviral inhibition of apoptosis protein repeat) domain and a UBCc (ubiquitin-conjugating enzyme E2, catalytic) domain. This protein inhibits apoptosis by facilitating the degradation of apoptotic proteins by ubiquitination.

Gene names and symbols associated with BIRC6

  • baculoviral IAP repeat containing 6 (BIRC6) anticorps
  • baculoviral IAP repeat-containing 6 (BIRC6) anticorps
  • baculoviral IAP repeat-containing 6 (birc6) anticorps
  • baculoviral IAP repeat containing 6 (birc6) anticorps
  • baculoviral IAP repeat-containing 6 (Birc6) anticorps
  • A430032G04Rik anticorps
  • A430040A19Rik anticorps
  • AA501170 anticorps
  • APOLLON anticorps
  • BIRC6 anticorps
  • Bruce anticorps
  • D630005A10Rik anticorps
  • mKIAA1289 anticorps

Protein level used designations for BIRC6

baculoviral IAP repeat-containing 6 (apollon) , baculoviral IAP repeat-containing 6 , BIR repeat-containing ubiquitin-conjugating enzyme , baculoviral IAP repeat-containing protein 6 , ubiquitin-conjugating BIR domain enzyme apollon , ubiquitin-conjugating BIR-domain enzyme apollon , apollon , baculovirus inhibitor of apoptosis repeat containing ubiquitin-conjugating enzyme , baculovirus inhibitor of apoptosis repeat containing ubiquitin-conjugating enzyme; accccbaculoviral IAP repeat-containing 6

GENE ID SPECIES
421463 Gallus gallus
475718 Canis lupus familiaris
709443 Macaca mulatta
720431 Macaca mulatta
796547 Danio rerio
100027051 Monodelphis domestica
100070568 Equus caballus
100079899 Ornithorhynchus anatinus
100135722 Xenopus (Silurana) tropicalis
100225419 Taeniopygia guttata
100342432 Oryctolagus cuniculus
100448259 Pongo abelii
100484115 Ailuropoda melanoleuca
57448 Homo sapiens
534211 Bos taurus
12211 Mus musculus
313876 Rattus norvegicus
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