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anti-Germ Cell Associated 2 (Haspin) (GSG2) Anticorps

Serine/threonine-protein kinase that phosphorylates histone H3 at 'Ser-3' (H3T3ph) during mitosis. De plus, nous expédions Germ Cell Associated 2 (Haspin) Protéines (5) et et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
GSG2 83903 Q8TF76
GSG2 687827  
GSG2 14841 Q9Z0R0
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Top anti-Germ Cell Associated 2 (Haspin) Anticorps sur anticorps-enligne.fr

Showing 10 out of 44 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué IHC (p), WB Haspin Antibody (R330) (ABIN1882168) western blot analysis in Daudi,Raji cell line lysates (35 µg/lane). This demonstrates the Haspin antibody detected the Haspin protein (arrow). Haspin Antibody (R330) (ABIN1882168) western blot analysis in Daudi,Raji cell line lysates (35 µg/lane). This demonstrates the Haspin antibody detected the Haspin protein (arrow). 400 μL Connectez-vous pour afficher 14 to 16 Days
335,24 €
Détails
Humain Lapin Inconjugué WB <b>WB Suggested Anti-GSG2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>721_B cell lysate WB Suggested Anti-GSG2 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control:.21_B cell lysate 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Humain Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Humain Lapin Inconjugué IHC, IHC (p), IP, WB 0.1 mL Connectez-vous pour afficher 6 to 8 Days
484,00 €
Détails
Humain Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 11 to 14 Days
653,02 €
Détails
Souris Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 11 to 14 Days
653,02 €
Détails
Humain Lapin Alkaline Phosphatase (AP) IHC, ELISA   200 μL Connectez-vous pour afficher 11 to 14 Days
1.019,69 €
Détails
Humain Lapin Inconjugué ELISA   200 μL Connectez-vous pour afficher 11 to 14 Days
845,08 €
Détails
Humain Lapin FITC IF (p)   100 μL Connectez-vous pour afficher 14 to 17 Days
366,11 €
Détails
Humain Lapin Alexa Fluor 350 IF (p)   100 μL Connectez-vous pour afficher 14 to 17 Days
366,11 €
Détails

GSG2 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité
Human , , , ,
,
Rat (Rattus) , ,

Mouse (Murine) , ,

anti-Germ Cell Associated 2 (Haspin) Anticorps mieux référencés

  1. Human Polyclonal GSG2 Primary Antibody pour IHC (p), WB - ABIN1882168 : Dai, Sultan, Taylor, Higgins: The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment. dans Genes & development 2005 (PubMed)
    Show all 3 references for ABIN1882168

Plus d’anticorps contre Germ Cell Associated 2 (Haspin) partenaires d’interaction

Fruit Fly (Drosophila melanogaster) Germ Cell Associated 2 (Haspin) (GSG2) interaction partners

Human Germ Cell Associated 2 (Haspin) (GSG2) interaction partners

  1. Haspin kinase plays a key role in maintaining the slowly exchanging centromere Borealin (Montrer CDCA8 Anticorps) pool.

  2. Haspin activity affects the phosphorylation state of proteins involved in gene expression regulation and splicing.

  3. Haspin inhibitors reveal centromeric roles of Aurora B (Montrer AURKB Anticorps) in chromosome movement and spindle checkpoint signaling

  4. Aurora B (Montrer AURKB Anticorps) phosphorylates Haspin to promote generation of H3T3ph and that Aurora B kinase (Montrer AURKB Anticorps) activity is required for normal chromosomal localization of the CPC, indicating an intimate linkage between Aurora B (Montrer AURKB Anticorps) and Haspin functions in mitosis

  5. findings show phosphorylation of histone H3-threonine 3 mediated by Haspin cooperates with Bub1-mediated histone 2A-serine 121 phosphorylation in targeting the chromosomal passenger complex to the inner centromere in fission yeast and human cells

  6. phosphorylation of H3T3 by Haspin is necessary for chromosomal passenger complex(CPC) accumulation at centromeres; Survivin (Montrer BIRC5 Anticorps) binds to H3T3ph; H3T3ph generated by Haspin positions CPC at centromeres to regulate selected targets of Aurora B (Montrer AURKB Anticorps) during mitosis

  7. Haspin-depleted cells reveal that spindle-pole integrity in mitosis requires chromosome cohesion.

  8. Haspin is a relatively newly discovered kinase that phosphorylates histone H3 (Montrer HIST3H3 Anticorps) during mitosis and appears to play a role in regulating chromosome behavior during cell division. [REVIEW]

  9. This work reveals a new kinase involved in composing the histone code and adds haspin to the select group of kinases that integrate regulation of chromosome and spindle function during mitosis and meiosis

  10. Haspin is required to maintain centromeric cohesion during mitosis.

Mouse (Murine) Germ Cell Associated 2 (Haspin) (GSG2) interaction partners

  1. Data implicate haspin as a regulator of the chromosomal passenger complex and chromosome segregation during meiosis I.

  2. the tissue-dependent and differentially methylated region functions as a modulator in a DNA methylation (Montrer HELLS Anticorps)-dependent manner; Gsg2 is under epigenetic control

  3. the 193-bp DNA sequence in Haspin promotor is sufficient for the specific, bidirectional, and synchronous expression in germ cells in the testis.

Germ Cell Associated 2 (Haspin) (GSG2) profil antigène

Profil protéine

Serine/threonine-protein kinase that phosphorylates histone H3 at 'Ser-3' (H3T3ph) during mitosis. This positions and activates AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle (By similarity).

Gene names and symbols associated with GSG2

  • serine/threonine-protein kinase haspin-like protein (Haspin) anticorps
  • germ cell associated 2 (haspin) (GSG2) anticorps
  • CG40080 gene product from transcript CG40080-RA (Haspin) anticorps
  • putative serine/threonine-protein kinase haspin homolog (Haspin) anticorps
  • germ cell associated 2 (haspin) (Gsg2) anticorps
  • germ cell-specific gene 2 (Gsg2) anticorps
  • BcDNA:LD07633 anticorps
  • CG40080 anticorps
  • Dmel\\CG40080 anticorps
  • Haspin anticorps
  • NV16901 anticorps

Protein level used designations for GSG2

serine/threonine-protein kinase haspin-like protein , germ cell associated 2 (haspin) , haspin , CG40080-PA , Haspin-PA , putative serine/threonine-protein kinase haspin homolog , H-haspin , germ cell-specific gene 2 protein , haploid germ cell-specific nuclear protein kinase , serine/threonine-protein kinase haspin

GENE ID SPECIES
552287 Apis mellifera
748101 Pan troglodytes
3355064 Drosophila melanogaster
100122327 Nasonia vitripennis
83903 Homo sapiens
767819 Bos taurus
687827 Rattus norvegicus
14841 Mus musculus
Fournisseurs de qualité sélectionnés pour anti-Germ Cell Associated 2 (Haspin) (GSG2) Anticorps
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