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The protein encoded by PTPRG is a member of the protein tyrosine phosphatase (PTP) family. De plus, nous expédions PTPRG Protéines (8) et PTPRG Kits (5) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 38 products:
Human Polyclonal PTPRG Primary Antibody pour IHC (p), IHC - ABIN315043
Nikolaienko, Hammel, Dubreuil, Zalmai, Hall, Mehzabeen, Karuppan, Harroch, Stella, Bouyain: Structural Basis for Interactions Between Contactin Family Members and Protein-tyrosine Phosphatase Receptor Type G in Neural Tissues. dans The Journal of biological chemistry 2016
Co-localization experiments performed with both anti-PTPRG antibodies identified the presence of isoforms and confirmed protein downregulation at diagnosis in the Philadelphia-positive myeloid lineage (including CD34 (Montrer CD34 Anticorps)+/CD38bright/dim cells).
family-based GWAS of imputed SNPs revealed novel genomic variants in (or near) PTPRG, OSBPL6 (Montrer OSBPL6 Anticorps), and PDCL3 (Montrer PDCL3 Anticorps) that influence risk for Alzheimer's Disease. rs7609954 in the gene PTPRG, rs1347297 in the gene OSBPL6 (Montrer OSBPL6 Anticorps), and rs1513625 near PDCL3 (Montrer PDCL3 Anticorps). In addition, rs72953347 in OSBPL6 (Montrer OSBPL6 Anticorps) and two SNPs in the gene CDKAL1 (Montrer CDKAL1 Anticorps) showed marginally significant association with LOAD (rs10456232, P-value=4.76 x 10-7; rs62400067, P-value=3.54 x 10-7).
Results demonstrate that PTPRG plasmatic form (sPTPRG) represent a novel candidate protein biomarker in plasma whose increased expression is associated to hepatocyte damage.
Our results showed that there was no significant association between any of five reported SNPs of TCF4 (Montrer TCF4 Anticorps) and PTPRG genes and the occurrence of Fuchs' endothelial dystrophy; only rs7640737 in PTPRG showed an increased risk for corneal dystrophy.
SNPs in PTPRG were not associated with FCD in Caucasians.
PTPRG is a JAK2 (Montrer JAK2 Anticorps) phosphatase that negatively regulates leukocyte integrin beta2 activation.
Mutations in PDGFRB (Montrer PDGFRB Anticorps) cause infantile myofibromatosis while a mutation in PTPRG may act as an aggravating factor.
Germline polymorphisms in PTPRG gene is associated with lung adenocarcinoma.
PTPRG expression induces dephosphorylation of ERK, a downstream RAS target that may be critical for mutant RAS-induced cell growth.
found that the RPTP-gamma, RPTP-gamma(V948I, S970T) and RPTP-gamma(C858S, S970T) proteins could be stored at 193 K in their respective crystallization buffers without affecting crystallization or crystal quality
vasoconstriction promoted through RPTPgamma-dependent changes in VSMC Ca(2 (Montrer CA2 Anticorps)+)-sensitivity
Protein-tyrosine phosphatase receptor type G (RPTPgamma/PTPRG) interacts in vitro with contactin-3 (Montrer CNTN3 Anticorps)-6 (CNTN3 (Montrer CNTN3 Anticorps)-6), a group of glycophosphatidylinositol-anchored cell adhesion molecules involved in the wiring of the nervous system
confirm previous findings and enrich the current knowledge of RPTPgamma distribution in the CNS, highlighting a role of RPTPgamma during neuroinflammation processes
RPTPgamma is expressed in a variety of tissues during embryogenesis.
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene.
, protein tyrosine phosphatase gamma
, protein tyrosine phosphatase, receptor type, gamma polypeptide
, protein-tyrosine phosphatase gamma
, receptor type protein tyrosine phosphatase gamma
, receptor tyrosine phosphatase gamma
, receptor-type protein phosphatase gamma
, receptor-type tyrosine-protein phosphatase gamma
, Protein-tyrosine phosphatase gamma precursor (R-PTP-gamma)
, RPTP gamma A
, RPTP gamma B
, RPTP gamma C
, RPTP gamma S
, receptor-like protein tyrosine phosphatase gamma