Smith-Magenis Syndrome Chromosome Region, Candidate 7 Protéines (SMCR7)

SMCR7 encodes an outer mitochondrial membrane protein that functions in the regulation of mitochondrial morphology. De plus, nous expédions SMCR7 Anticorps (7) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
SMCR7 125170 Q96C03
Souris SMCR7 SMCR7 237781 Q5NCS9
SMCR7 443935  
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Showing 3 out of 3 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher 10 to 12 Days
$785.40
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$405.71
Détails
Levure Xenopus laevis His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$3,157.00
Détails

SMCR7 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human ,
,
Xenopus laevis

Plus protéines pour Smith-Magenis Syndrome Chromosome Region, Candidate 7 (SMCR7) partenaires d'interaction

Human Smith-Magenis Syndrome Chromosome Region, Candidate 7 (SMCR7) interaction partners

  1. MiD49 and MiD51 recruit inactive forms of Drp1 in mitochondrial fission. [review]

  2. These findings and data showing MARCH5 (Montrer MARCH5 Protéines)-dependent degradation of MiD49 upon stress support the possibility that MARCH5 (Montrer MARCH5 Protéines) regulation of MiD49 is a novel mechanism controlling mitochondrial fission and, consequently, the cellular response to stress.

  3. The results indicate that Drp1 (Montrer CRMP1 Protéines)-dependent mitochondrial fission through MiD49/MiD51 (Montrer SMCR7L Protéines) regulates cristae remodeling during intrinsic apoptosis.

  4. MIEF1 (Montrer SMCR7L Protéines) and MIEF2 are differentially expressed in human tissues during development

  5. MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and suggest that they provide specificity to the division of mitochondria.

  6. we find that either MiD49 or MiD51 (Montrer SMCR7L Protéines) can mediate Drp1 (Montrer CRMP1 Protéines) recruitment and mitochondrial fission in the absence of Fis1 (Montrer FIS1 Protéines) and Mff (Montrer MFF Protéines).

  7. Mitochondrial outer membrane protein that recruits fission mediator Drp1 to the mitochondrial surface.

Mouse (Murine) Smith-Magenis Syndrome Chromosome Region, Candidate 7 (SMCR7) interaction partners

  1. MiD51 (Montrer SMCR7L Protéines) can suppress Mff (Montrer MFF Protéines)-dependent enhancement of Drp1 (Montrer CRMP1 Protéines) GTPase (Montrer RACGAP1 Protéines) activity.

  2. This paper combines confocal live-cell imaging with correlative cryogenic fluorescence microscopy and soft x-ray tomography to link MiD49 and MiD51 (Montrer SMCR7L Protéines) to the involvement of the endoplasmic reticulum in mitochondrial fission.

  3. Determined the crystal structure and fperformed unctional analysis of mouse MiD49.

  4. MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and suggest that they provide specificity to the division of mitochondria.

Profil protéine SMCR7

Profil protéine

This gene encodes an outer mitochondrial membrane protein that functions in the regulation of mitochondrial morphology. It can directly recruit the fission mediator dynamin-related protein 1 (Drp1) to the mitochondrial surface. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with SMCR7

  • mitochondrial elongation factor 2 (MIEF2)
  • mitochondrial elongation factor 2 S homeolog (mief2.S)
  • mitochondrial elongation factor 2 (Mief2)
  • AI482195 Protéine
  • Gm11 Protéine
  • mid49 Protéine

Protein level used designations for SMCR7

Smith-Magenis syndrome chromosomal region candidate gene 7 protein , mitochondrial dynamic protein MID49 , mitochondrial dynamic protein of 49 kDa , Smith-Magenis syndrome chromosomal region candidate gene 7 protein homolog , mitochondrial dynamic protein of 49 kDa homolog , smith-Magenis syndrome chromosomal region candidate gene 7 protein homolog

GENE ID SPECIES
125170 Homo sapiens
443935 Xenopus laevis
237781 Mus musculus
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