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The protein encoded by THBS1 is a subunit of a disulfide-linked homotrimeric protein. De plus, nous expédions Thrombospondin 1 Kits (55) et Thrombospondin 1 Protéines (41) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 173 products:
Cow (Bovine) Monoclonal Thrombospondin 1 Primary Antibody pour IP, WB - ABIN197629
Frazier: Thrombospondin: a modular adhesive glycoprotein of platelets and nucleated cells. dans The Journal of cell biology 1987
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Cow (Bovine) Monoclonal Thrombospondin 1 Primary Antibody pour Func, FACS - ABIN180505
Galvin, Dixit, ORourke, Santoro, Grant, Frazier: Mapping of epitopes for monoclonal antibodies against human platelet thrombospondin with electron microscopy and high sensitivity amino acid sequencing. dans The Journal of cell biology 1985
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Cow (Bovine) Monoclonal Thrombospondin 1 Primary Antibody pour BP, ICC - ABIN151527
Cupi, Sarra, De Nitto, Franzè, Marafini, Monteleone, Del Vecchio Blanco, Paoluzi, Di Fusco, Gentileschi, Ortenzi, Colantoni, Pallone, Monteleone: Defective expression of scavenger receptors in celiac disease mucosa. dans PLoS ONE 2014
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Mammalian Monoclonal Thrombospondin 1 Primary Antibody pour IF, IHC (p) - ABIN115006
Dixit, Haverstick, ORourke, Hennessy, Grant, Santoro, Frazier: Effects of anti-thrombospondin monoclonal antibodies on the agglutination of erythrocytes and fixed, activated platelets by purified thrombospondin. dans Biochemistry 1985
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Cow (Bovine) Monoclonal Thrombospondin 1 Primary Antibody pour FACS, IF - ABIN180348
Prater, Plotkin, Jaye, Frazier: The properdin-like type I repeats of human thrombospondin contain a cell attachment site. dans The Journal of cell biology 1991
ELL (Montrer ELL Anticorps) (Eleven-Nineteen Lysine-rich Leukemia) acts as a transcription factor for direct thrombospondin-1 regulation
Within the limitations of this study, the results seem to sustain the involvement of Pentraxin 3 (Montrer PTX3 Anticorps) and Thrombospondin 1 in the processes of inflammation and angiogenesis in wound healing of patients with postorthodontic gingivectomy.
Results identified CRISP2 (Montrer CRISP2 Anticorps) as a potential binding protein of PSP94 (Montrer MSMB Anticorps) from human sperm.
Circulating TSP-1 levels decrease up to 24 months prior to diagnosis of PDAC and significantly enhance the diagnostic performance of CA19-9. The influence of diabetes mellitus on biomarker behavior should be considered in future studies.
Crisp2 (Montrer CRISP2 Anticorps) genetic defects in sperm from humans and mice result in male infertility.
F-actin dynamics modulate the patterning of TSP1 in extracellular matrix and that TSP1 oligomer state is a key determinant of this process.
TSP-1 regulates multiple microRNAs in VSMCs adding a new layer of complexity to TSP-1 regulation of VSMC function
quercetin could increase TSP-1 expression to inhibit angiogenesis resulting in antagonizing prostate cancer PC-3 (Montrer PCSK1 Anticorps) cell and xenograft tumor growth
The anti-angiogenic activity of the native TSP-1 active fragment was maintained in the new TSP-1 mimetics and the results provide a new chemical approach for the design of TSP-1 mimetics.
In the current study Factor V Leiden (Montrer F5 Anticorps), prothrombin (Montrer F2 Anticorps) G20210A, and thrombospondin-1 polymorphisms showed no association with severity of hepatic fibrosis.
Triptolide can down regulates the expression of thrombospondin 1 and TGF-beta-1 (Montrer TGFB1 Anticorps) in renal tubular cells. This plays a role in the pathogenesis of renal tubular fibrosis.
Data suggest THBS1 expression predominates in luteal endothelial cells; THBS2 (Montrer THBS2 Anticorps) expression predominates in luteinized granulosa cells. Luteinization down-regulates expression of THBS1/THBS2 (Montrer THBS2 Anticorps), up-regulates expression of FGF2 (fibroblast growth factor 2 (Montrer FGF2 Anticorps)).
Thrombospondin has a role in inducing RhoA (Montrer RHOA Anticorps) inactivation through FAK (Montrer PTK2 Anticorps)-dependent signaling to stimulate focal adhesion disassembly
Thrombospondin-1 and -2 were coordinately expressed in the extravascular compartment of the ovary during early follicle development. VEGF was inversely expressed, with expression increasing as follicles developed.
Preincubation of erythroid cells with thrombospondin 1 eliminated the inhibitory activity of insulin (Montrer INS Anticorps)-like growth factor
The cell-specific regulation of TSP-1 suggests a potential mechanism for the aberrant angiogenesis in diabetics and TSP-1 involvement in development of various vascular diabetic complications
The novel finding that TSP-1-induced migration is dependent on the CD44 (Montrer CD44 Anticorps) receptor links 2 pathways thought to be disparate (ie, TSP-1 and HyA (Montrer KDM5D Anticorps)).
Data indicate that thrombospondin-1 may contribute to a destructive macrophage response in dysferlinopathy and pose the intriguing possibility that thrombospondin-1 levels may serve as a biomarker for disease progression.
demonstrate that HIF-2alpha (Montrer EPAS1 Anticorps) is clearly implicated in the TSP1 (Montrer GZMA Anticorps) pulmonary regulation and provide new insights on its contribution to pulmonary arterial hypertension-driven vascular remodelling and vasoconstriction
Thrombospondin-1 was differentially expressed according to tumor grade, but not affected by p53 (Montrer TP53 Anticorps) expression or mutational status
Data suggest neutrophil protease- Tsp-1 (thrombospondin-1) axis as a potential antimetastatic therapeutic target.
These results contribute new insights on the controversial role of TSP-1 (Montrer GZMA Anticorps) in cancer.
TSP1 (Montrer GZMA Anticorps) contributes to progression of chronic kidney disease by catalyzing activation of latent TGF-beta1 (Montrer TGFB1 Anticorps), resulting in promotion of a fibroproliferative response over an inflammatory response.
Thrombospondin1 deficiency did not affect the development of obesity associated macro-vascular complication in ApoE (Montrer APOE Anticorps)-/- mice, but attenuated obesity associated micro-vascular complications.
Thrombospondin-1 expression plays a significant role in regulation of migration and adhesion of mononuclear cells, contributing to vascular inflammation during AAA (Montrer AAAS Anticorps) development.
findings prove that the TSP-1 (Montrer GZMA Anticorps)/CD47 (Montrer CD47 Anticorps)/SIRP (Montrer SIRPA Anticorps)-alpha signal axis is important to the evolution of tumor cells in the microenvironment of immunotherapy and identify thrombospondin-1 as a key signal
ADAMTS-7 (Montrer ADAMTS7 Anticorps) was directly associated with thrombospondin-1 by its C terminus and degraded thrombospondin-1 in vivo and in vitro. The inhibitory effect of ADAMTS-7 (Montrer ADAMTS7 Anticorps) on postinjury endothelium recovery was circumvented in Tsp1 (Montrer GZMA Anticorps)(-/-) mice.
These current studies were undertaken to determine how TSP-1 functions to modulate the smooth muscle cell response to IGF-I (Montrer IGF1 Anticorps) and the mechanisms by which hyperglycemia regulates TSP-1 protein.
Increased TSP-1 expression in non-heart-beating donors may indicate a compensatory response to the reported diminished TGF-beta1 (Montrer TGFB1 Anticorps) expression.
The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis.
, cancer/testis antigen 36
, glyceraldehyde-3-phosphate dehydrogenase-like 5
, testis specific protein 1 (probe H4-1 p3-1)
, testis-specific protein TPX-1