You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Transcription Factor 12 (TCF12) Anticorps

The protein encoded by TCF12 is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. De plus, nous expédions TCF12 Protéines (7) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
TCF12 6938 Q99081
TCF12 21406 Q61286
TCF12 25720 P51514
Comment commander chez anticorps-enligne
  • +33 (0)1 76 63 32 65
  • +33 (0)1 74 18 08 22
  • Commandez enligne
  • orders@anticorps-enligne.fr

Top anti-TCF12 Anticorps sur anticorps-enligne.fr

Showing 10 out of 89 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-TCF12 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Jurkat cell lysate WB Suggested Anti-TCF12  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: Jurkat cell lysate  TCF12 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Poulet Lapin Inconjugué WB WB Suggested Anti-TCF12 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Hela cell lysate 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Poulet Lapin Inconjugué WB WB Suggested Anti-TCF12 Antibody Titration: 0.06ug/mlELISA Titer: 1:1562500Positive Control: Human Lung Host: Rabbit  Target Name: TCF12  Sample Tissue: Human Fetal Brain  Antibody Dilution: 1.0 µg/mL 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Humain Lapin Inconjugué EIA, WB TCF12 Antibody (N-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the TCF12 antibody detected the TCF12 protein (arrow). 0.4 mL Connectez-vous pour afficher 8 to 10 Days
407,00 €
Détails
Humain Lapin Inconjugué EIA, WB Western blot analysis of TCF12 in HeLa cell lysate with TCF12 antibody at (A) 0.5 and (B) 1 μg/ml. 0.1 mg Connectez-vous pour afficher 8 to 10 Days
357,50 €
Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Humain Souris Inconjugué IF, WB Immunofluorescence of monoclonal antibody to TCF12 on HeLa cell (antibody concentration 10 µg/mL). Western Blot analysis of TCF12 expression in transfected 293T cell line by TCF12 monoclonal antibody (M01), clone 2E9. Lane 1: TCF12 transfected lysate(75.8 KDa). Lane 2: Non-transfected lysate. 0.1 mg Connectez-vous pour afficher 12 to 16 Days
454,76 €
Détails
Humain Lapin Inconjugué ELISA, WB 50 μg Connectez-vous pour afficher 6 to 8 Days
459,65 €
Détails
Humain Lapin Inconjugué ELISA, WB 50 μg Connectez-vous pour afficher 6 to 8 Days
459,65 €
Détails
Humain Lapin Inconjugué EIA, IHC (p), WB Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Connectez-vous pour afficher 8 to 10 Days
517,00 €
Détails

TCF12 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
Human , , ,
,
,
, , , , , , , , , , , , , ,
Mouse (Murine) ,


, , , , , , , , , , ,
Rat (Rattus) ,


, , , , , , , , , , ,

anti-TCF12 Anticorps mieux référencés

  1. Cow (Bovine) Polyclonal TCF12 Primary Antibody pour WB - ABIN2780487 : Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France. dans Diagnostic microbiology and infectious disease 2006 (PubMed)
    Show all 2 references for ABIN2780487

  2. Human Polyclonal TCF12 Primary Antibody pour EIA, WB - ABIN783743 : Murre, McCaw, Vaessin, Caudy, Jan, Jan, Cabrera, Buskin, Hauschka, Lassar: Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence. dans Cell 1989 (PubMed)
    Show all 2 references for ABIN783743

  3. Chicken Polyclonal TCF12 Primary Antibody pour WB - ABIN2774659 : Wissmüller, Kosian, Wolf, Finzsch, Wegner: The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors. dans Nucleic acids research 2006 (PubMed)
    Show all 2 references for ABIN2774659

  4. Human Polyclonal TCF12 Primary Antibody pour EIA, WB - ABIN955126 : Schotte, Dontje, Nagasawa, Yasuda, Bakker, Spits, Blom: Synergy between IL-15 and Id2 promotes the expansion of human NK progenitor cells, which can be counteracted by the E protein HEB required to drive T cell development. dans Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)

Plus d’anticorps contre TCF12 partenaires d’interaction

Human Transcription Factor 12 (TCF12) interaction partners

  1. Two novel translocations leading to the inactivation of RUNX1 (Montrer RUNX1 Anticorps) and its partners SIN3A (Montrer SIN3A Anticorps) and TCF12 in myeloid leukemia (Montrer BCL11A Anticorps).

  2. Studies suggest that transcription factor 12 (TCF12) should be included in level 2 genetic testing.

  3. show that these mutations compromise TCF12 transcriptional activity and are associated with a more aggressive tumour type

  4. several familial cases of coronal synostosis associated with mutations in TCF12

  5. In t(8;21) leukemia cells, the two E proteins, HEB and E2A (Montrer TCF3 Anticorps), function as components of the stable AML1 (Montrer RUNX1 Anticorps)-ETO (Montrer RUNX1T1 Anticorps)-containing transcription factor complex (AETFC). The AETFC components cooperatively regulate gene expression and contribute to leukemogenesis.

  6. haploinsufficiency of TCF12 causes coronal synostosis in humans and that severe bilateral coronal synostosis occ (Montrer TWIST1 Anticorps)urs in mice with 50% of the wild-type dosage of both the T (Montrer TWIST1 Anticorps)cf12 and Twist1 genes highlights the key role of TCF12 acting with TWIST1.

  7. the CD91 (Montrer LRP1 Anticorps)/IKK (Montrer CHUK Anticorps)/NF-kappaB (Montrer NFKB1 Anticorps) signaling cascade is involved in secreted HSP90alpha (Montrer HSP90AA2 Anticorps)-induced TCF12 expression, leading to E-cadherin (Montrer CDH1 Anticorps) down-regulation and enhanced CRC (Montrer CALR Anticorps) cell migration/invasion

  8. TCF12 functioned as a transcriptional repressor of E-cadherin (Montrer CDH1 Anticorps) and its overexpression was significantly correlated with the occurrence of CRC (Montrer CALR Anticorps) metastasis.

  9. HEB and E2A (Montrer TCF3 Anticorps)-bind the SCA motif at regions overlapping SMAD2 (Montrer SMAD2 Anticorps)/3 and FOXH1 (Montrer FOXH1 Anticorps)

  10. As a first exploitation of this unique cohort, we identify three novel candidate dyslexia genes, ZNF280D (Montrer ZNF280D Anticorps) and TCF12 at 15q21, and PDE7B (Montrer PDE7B Anticorps) at 6q23.3, by molecular mapping of the familial translocation with the 15q21 breakpoint.

Mouse (Murine) Transcription Factor 12 (TCF12) interaction partners

  1. HEB (Montrer FREM1 Anticorps) is a fundamental link between Nodal signalling, the derepression of a specific class of poised promoters during differentiation, and lineage specification in mouse embryonic stem cells

  2. severe bilateral coronal synostosis occurs in mice with 50% of the wild-type dosage of both the Tcf12 and Twist1 (Montrer TWIST1 Anticorps) genes highlights the key role of TCF12 acting with TWIST1 (Montrer TWIST1 Anticorps) in the normal development of the coronal sutures

  3. Deficiency in the E proteins, E2A (Montrer TCF3 Anticorps) and HEB (Montrer FREM1 Anticorps), led to increased frequency of terminally differentiated effector KLRG1 (Montrer KLRG1 Anticorps)(hi) CD8 (Montrer CD8A Anticorps)(+) T cells in mice during infection, and decreased generation of longer-lived memory-precursor cells during the immune response.

  4. Deletion of HEB (Montrer FREM1 Anticorps) and E2A (Montrer TCF3 Anticorps) in DP thymocytes specifically blocked the development of CD4 (Montrer CD4 Anticorps)(+) lineage T cells. Furthermore, deletion of the E protein inhibitors Id2 and Id3 (Montrer ID3 Anticorps) allowed CD4 (Montrer CD4 Anticorps)(+) T cell development but blocked CD8 (Montrer CD8A Anticorps)(+) lineage development.

  5. the earliest event in B-cell specification involves the induction of FOXO1 (Montrer FOXO1 Anticorps) expression and requires the combined activities of E2A (Montrer TCF3 Anticorps) and HEB (Montrer FREM1 Anticorps)

  6. These results showed a new set of interactions between HEB (Montrer FREM1 Anticorps), Notch1 (Montrer NOTCH1 Anticorps), and GATA3 (Montrer GATA3 Anticorps) that regulate the T-cell fate choice in developing thymocytes.

  7. Developmental progression of fetal HEB (Montrer FREM1 Anticorps)(-/-) precursors to the pre-T-cell stage is restored by HEBAlt.

  8. HEB (Montrer FREM1 Anticorps) is a specific and essential factor in T-cell development and in the generation of the iNKT cell lineage.

  9. the dosage of HEB (Montrer FREM1 Anticorps) determines pT alpha (Montrer PTCRA Anticorps) gene expression in immature T cells

  10. the Tcf12 gene may be involved in the control of proliferating neural stem cells and progenitor cells

TCF12 profil antigène

Profil protéine

The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. This encoded protein is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Gene names and symbols associated with TCF12

  • transcription factor 12 (TCF12) anticorps
  • transcription factor 12 (LOC100339415) anticorps
  • transcription factor 12 (tcf12) anticorps
  • transcription factor 12 (Tcf12) anticorps
  • transcription factor 12 (HTF4, helix-loop-helix transcription factors 4) (tcf12) anticorps
  • A130037E08Rik anticorps
  • ALF1 anticorps
  • bHLHb20 anticorps
  • CRS3 anticorps
  • HEB anticorps
  • HEBAlt anticorps
  • HsT17266 anticorps
  • HTF-4 anticorps
  • HTF4 anticorps
  • ME1 anticorps
  • REB anticorps
  • SCBPA anticorps
  • TCF12 anticorps
  • wu:fb74g05 anticorps
  • wu:fc43e06 anticorps
  • zgc:85956 anticorps
  • zgc:110341 anticorps

Protein level used designations for TCF12

transcription factor 12 , transcription factor 12 (HTF4, helix-loop-helix transcription factors 4) , DNA-binding protein HTF4 , E-box-binding protein , TCF-12 , class B basic helix-loop-helix protein 20 , helix-loop-helix transcription factor 4 , transcription factor HTF-4 , class A helix-loop-helix transcription factor ME1 , SCBP alpha , SCBP-alpha , salivary-specific cAMP response element-binding protein alpha , TF12 , basic helix-loop-helix protein , class A helix-loop-helix transcription factor GE1 , XE1.1

GENE ID SPECIES
453466 Pan troglodytes
100339415 Oryctolagus cuniculus
100460448 Pongo abelii
100553875 Anolis carolinensis
100603993 Nomascus leucogenys
6938 Homo sapiens
509039 Bos taurus
21406 Mus musculus
25720 Rattus norvegicus
407985 Danio rerio
396334 Gallus gallus
100684199 Canis lupus familiaris
399451 Xenopus laevis
Fournisseurs de qualité sélectionnés pour anti-TCF12 (TCF12) Anticorps
Avez-vous cherché autre chose?